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Tmem68 Gene Detail
Summary
  • Symbol
    Tmem68
  • Name
    transmembrane protein 68
  • Synonyms
    2010300G19Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919348
    NCBI Gene: 72098
Location & Maps
more
  • Genetic Map
    Chromosome 4, 1.98 cM
  • Mapping Data
    1 experiment
Homology
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  • Human Ortholog
    TMEM68, transmembrane protein 68
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TMEM68, transmembrane protein 68
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 137695
    neXtProt AC: NX_Q96MH6

  • Chr Location
    8q12.1; chr8:55738744-55773407 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000004261 VEGA Gene Model | MGI Sequence Detail 25813 C57BL/6J ±  kb
transcript OTTMUST00000009645 VEGA | MGI Sequence Detail 2690 Not Applicable  
polypeptide OTTMUSP00000004655 VEGA | MGI Sequence Detail 329 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    165 from dbSNP Build 142
Protein
Information
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  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000032537 transmembrane protein 68
  • InterPro Domains
    IPR002123 Phospholipid/glycerol acyltransferase
Molecular
Reagents
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  • All nucleic 53
    cDNA 53

    Microarray probesets 3
Other
Accession IDs
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MGI:2140129, MGI:2140558
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/20/2016
MGI 6.05
The Jackson Laboratory