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Anks4b Gene Detail
Summary
  • Symbol
    Anks4b
  • Name
    ankyrin repeat and sterile alpha motif domain containing 4B
  • Synonyms
    2010013E14Rik, Harp
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919324
    NCBI Gene: 72074
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:119773081-119782939 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 64.45 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    32 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919324
protein coding gene Chr7:119773081-119784809 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032925
protein coding gene Chr7:124128980-124139427 (+)
A/J MGP_AJ_G0032908
protein coding gene Chr7:120910711-120920589 (+)
AKR/J MGP_AKRJ_G0032840
protein coding gene Chr7:124028892-124038750 (+)
BALB/cJ MGP_BALBcJ_G0032913
protein coding gene Chr7:120645789-120655608 (+)
C3H/HeJ MGP_C3HHeJ_G0032623
protein coding gene Chr7:123936410-123946306 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033419
protein coding gene Chr7:129025210-129035061 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030391
protein coding gene Chr7:122327796-122337647 (+)
CAST/EiJ MGP_CASTEiJ_G0031951
protein coding gene Chr7:115695859-115705910 (+)
CBA/J MGP_CBAJ_G0032596
protein coding gene Chr7:133353199-133362966 (+)
DBA/2J MGP_DBA2J_G0032748
protein coding gene Chr7:118961401-118971203 (+)
FVB/NJ MGP_FVBNJ_G0032701
protein coding gene Chr7:118788954-118799139 (+)
LP/J MGP_LPJ_G0032842
protein coding gene Chr7:125575506-125591386 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032733
protein coding gene Chr7:134792138-134803724 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033439
protein coding gene Chr7:123015473-123025315 (+)
PWK/PhJ MGP_PWKPhJ_G0031659
protein coding gene Chr7:111875940-111886188 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031505
protein coding gene Chr7:109760677-109770554 (+)
WSB/EiJ MGP_WSBEiJ_G0032064
protein coding gene Chr7:123904771-123916195 (+)



Homology
more
  • Human Ortholog
    ANKS4B, ankyrin repeat and sterile alpha motif domain containing 4B
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ANKS4B, ankyrin repeat and sterile alpha motif domain containing 4B
  • Synonyms
    HARP
  • Links
    NCBI Gene ID: 257629
    neXtProt AC: NX_Q8N8V4
    UniProt: Q8N8V4

  • Chr Location
    16p12.2; chr16:21233699-21253850 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72074 NCBI Gene Model | MGI Sequence Detail 9859 C57BL/6J ±  kb
    transcript NM_028085 RefSeq | MGI Sequence Detail 2048 ZRU/MplStud  
    polypeptide Q8K3X6 UniProt | EBI | MGI Sequence Detail 423 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 14
      cDNA 13
      Primer pair 1

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2142078
    References
    more
    • Summaries
      All 31
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 5
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:274872 Ingham NJ, et al., Mouse screen reveals multiple new genes underlying mouse and human hearing loss. PLoS Biol. 2019 Apr;17(4):e3000194

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory