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Slc5a11 Gene Detail
Summary
  • Symbol
    Slc5a11
  • Name
    solute carrier family 5 (sodium/glucose cotransporter), member 11
  • Synonyms
    2010013B02Rik, Kst1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919316
    NCBI Gene: 233836
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:122814003-122872476 bp, + strand
    From Ensembl annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 7, 67.42 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    413 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919316
 protein coding gene Chr7:122813817-122873612 (+)
129S1/SvImJ MGP_129S1SvImJ_G0032960
 protein coding gene Chr7:127356484-127416823 (+)
A/J MGP_AJ_G0032943
 protein coding gene Chr7:124043087-124104090 (+)
AKR/J MGP_AKRJ_G0032875
 protein coding gene Chr7:127201979-127264260 (+)
BALB/cJ MGP_BALBcJ_G0032948
 protein coding gene Chr7:123716798-123774459 (+)
C3H/HeJ MGP_C3HHeJ_G0032658
 protein coding gene Chr7:127108970-127171979 (+)
C57BL/6NJ MGP_C57BL6NJ_G0033454
 protein coding gene Chr7:132322685-132382194 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0030426
 protein coding gene Chr7:125336162-125399276 (+)
CAST/EiJ MGP_CASTEiJ_G0031986
 protein coding gene Chr7:118920998-118982052 (+)
CBA/J MGP_CBAJ_G0032631
 protein coding gene Chr7:136784308-136847093 (+)
DBA/2J MGP_DBA2J_G0032783
 protein coding gene Chr7:122028579-122087171 (+)
FVB/NJ MGP_FVBNJ_G0032736
 protein coding gene Chr7:121876711-121937357 (+)
LP/J MGP_LPJ_G0032877
 protein coding gene Chr7:128785150-128846700 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032768
 protein coding gene Chr7:138126766-138198241 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0033474
 protein coding gene Chr7:126201156-126260788 (+)
PWK/PhJ MGP_PWKPhJ_G0031694
 protein coding gene Chr7:114972308-115034078 (+)
SPRET/EiJ MGP_SPRETEiJ_G0031540
 protein coding gene Chr7:112973393-113035210 (+)
WSB/EiJ MGP_WSBEiJ_G0032099
 protein coding gene Chr7:127110815-127171775 (+)



Homology
more
  • Human Ortholog
    SLC5A11, solute carrier family 5 member 11
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    SLC5A11, solute carrier family 5 member 11
  • Synonyms
    KST1, RKST1, SGLT6, SMIT2
  • Links
    NCBI Gene ID: 115584
    neXtProt AC: NX_Q8WWX8
    UniProt: Q8WWX8

  • Chr Location
    16p12.1; chr16:24845841-24911628 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    17
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    716
  • Tissues
    3
  • cDNA Data
    15
  • Literature Summary
    3
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000030769 Ensembl Gene Model | MGI Sequence Detail 58474 C57BL/6J ±  kb
transcript ENSMUST00000167299 Ensembl | MGI Sequence Detail 2022 Not Applicable  
polypeptide ENSMUSP00000127977 Ensembl | MGI Sequence Detail 673 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 15
    Primer pair 2

    Microarray probesets 3
References
more
  • Summaries
    All 40
    Developmental Gene Expression 3
    Gene Ontology 8
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:258659 Abbott GW, et al., KCNQ1, KCNE2, and Na+-coupled solute transporters form reciprocally regulating complexes that affect neuronal excitability. Sci Signal. 2014 Mar 4;7(315):ra22
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
04/16/2024
MGI 6.23 		The Jackson Laboratory