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2010111I01Rik Gene Detail
Summary
  • Symbol
    2010111I01Rik
  • Name
    RIKEN cDNA 2010111I01 gene
  • Synonyms
    2300006M17Rik, aminopeptidase O, ApO
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919311
    NCBI Gene: 72061
  • Alliance
    gene page
Location & Maps
more
  • Sequence Map
    Chr13:63282142-63326096 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser
  • Download
    Sequence
      43955 bp   ±  kb flank

  • Genome Browsers
    VEGA | Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 13, 32.80 cM, cytoband B3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    C9orf3, chromosome 9 open reading frame 3
  • Vertebrate Orthologs
    10
  • Human Ortholog
    C9orf3, chromosome 9 open reading frame 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    AOPEP, APO, AP-O, C90RF3, ONPEP
  • Links
    NCBI Gene ID: 84909
    neXtProt AC: NX_Q8N6M6
    UniProt: Q8N6M6

  • Chr Location
    9q22.32; chr9:94726604-95148264 (+)  GRCh38.p7
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Mice homozygous for one gene trapped allele are phenotypically normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    20
  • GO References
    8
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    33
  • Tissues
    17
  • cDNA Data
    25
  • Literature Summary
    1
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000030849 VEGA Gene Model | MGI Sequence Detail 43955 C57BL/6J ±  kb
transcript OTTMUST00000076332 VEGA | MGI Sequence Detail 2667 Not Applicable  
polypeptide OTTMUSP00000040169 VEGA | MGI Sequence Detail 114 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1841 from dbSNP Build 142
Protein
Information
less
  • UniProt
    16 Sequences
  • EC
    3.4.11.-
  • InterPro Domains
    IPR033577 Aminopeptidase O
    IPR016024 Armadillo-type fold
    IPR001930 Peptidase M1, alanine aminopeptidase/leukotriene A4 hydrolase
    IPR015211 Peptidase M1, leukotriene A4 hydrolase/aminopeptidase C-terminal
    IPR038502 Peptidase M1 LTA-4 hydrolase/aminopeptidase, C-terminal domain superfamily
    IPR014782 Peptidase M1, membrane alanine aminopeptidase, N-terminal
Molecular
Reagents
less
  • All nucleic 27
    Genomic 1
    cDNA 26

    Microarray probesets 7
Other
Accession IDs
less
MGI:1916716, MGI:2145468
References
more
  • Summaries
    All 42
    Developmental Gene Expression 1
    Gene Ontology 8
    Phenotypes 12
  • Earliest
    J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
  • Latest
    J:249029 Shen L, et al., MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes. PLoS One. 2016;11(2):e0148532
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
10/16/2018
MGI 6.12 		The Jackson Laboratory