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Aopep Gene Detail
Summary
  • Symbol
    Aopep
  • Name
    aminopeptidase O
  • Synonyms
    2010111I01Rik, 2300006M17Rik, ApO
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919311
    NCBI Gene: 72061
  • Alliance
  • Transcription Start Sites
    13 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:62964893-63326096 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 32.80 cM, cytoband B3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1841 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919311
protein coding gene Chr13:62964893-63326096 (+)
129S1/SvImJ MGP_129S1SvImJ_G0020668
protein coding gene Chr13:62962524-63286204 (+)
A/J MGP_AJ_G0020622
protein coding gene Chr13:60688853-60984362 (+)
AKR/J MGP_AKRJ_G0020599
protein coding gene Chr13:62710928-63026673 (+)
BALB/cJ MGP_BALBcJ_G0020620
protein coding gene Chr13:61108120-61412987 (+)
C3H/HeJ MGP_C3HHeJ_G0020415
protein coding gene Chr13:62243537-62559097 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021056
protein coding gene Chr13:65011365-65348338 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018632
protein coding gene Chr13:58366159-58658283 (+)
CAST/EiJ MGP_CASTEiJ_G0019932
protein coding gene Chr13:62251297-62561655 (+)
CBA/J MGP_CBAJ_G0020375
protein coding gene Chr13:67520816-67867841 (+)
DBA/2J MGP_DBA2J_G0020500
protein coding gene Chr13:60527721-60827280 (+)
FVB/NJ MGP_FVBNJ_G0020479
protein coding gene Chr13:59644084-59944776 (+)
LP/J MGP_LPJ_G0020574
protein coding gene Chr13:63248030-63563000 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020508
protein coding gene Chr13:66527269-66841064 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021098
protein coding gene Chr13:62015133-62331119 (+)
PWK/PhJ MGP_PWKPhJ_G0019686
protein coding gene Chr13:60080489-60385618 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019512
protein coding gene Chr13:60184978-60486744 (+)
WSB/EiJ MGP_WSBEiJ_G0019992
protein coding gene Chr13:62515612-62821346 (+)



Homology
more
  • Human Ortholog
    AOPEP, aminopeptidase O (putative)
  • Vertebrate Orthologs
    10
  • Human Ortholog
    AOPEP, aminopeptidase O (putative)
    Orthology source: HomoloGene, HGNC
  • Synonyms
    APO, AP-O, C90RF3, C9orf3, ONPEP
  • Links
    NCBI Gene ID: 84909
    neXtProt AC: NX_Q8N6M6
    UniProt: Q8N6M6

  • Chr Location
    9q22.32; chr9:94726604-95148264 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 66273
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: AOPEP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for one gene trapped allele are phenotypically normal.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 72061 NCBI Gene Model | MGI Sequence Detail 361204 C57BL/6J ±  kb
    transcript NM_001289926 RefSeq | MGI Sequence Detail 6778 C57BL/6  
    polypeptide Q8BXQ6 UniProt | EBI | MGI Sequence Detail 817 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 27
      Genomic 1
      cDNA 26

      Microarray probesets 7
    Other
    Accession IDs
    less
    MGI:1916716, MGI:2145468
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 1
      Gene Ontology 5
      Phenotypes 14
    • Earliest
      J:182573 Roderick TH, Producing and detecting paracentric chromosomal inversions in mice. Mutat Res. 1971 Jan;11(1):59-69
    • Latest
      J:249029 Shen L, et al., MicroRNA-27b Regulates Mitochondria Biogenesis in Myocytes. PLoS One. 2016;11(2):e0148532

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    02/23/2021
    MGI 6.16
    The Jackson Laboratory