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Mccc1 Gene Detail
Summary
  • Symbol
    Mccc1
  • Name
    methylcrotonoyl-Coenzyme A carboxylase 1 (alpha)
  • Synonyms
    1810045E08Rik, 2310058B18Rik, MCCA, MCCalpha
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919289
    NCBI Gene: 72039
Location & Maps
more
  • Sequence Map
    Chr3:35959312-36000678 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      41367 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 17.41 cM, cytoband B
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    MCCC1, methylcrotonoyl-CoA carboxylase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MCCC1, methylcrotonoyl-CoA carboxylase 1
    Orthology source: HomoloGene
  • Synonyms
    MCCA, MCC-B
  • Links
    NCBI Gene ID: 56922
    neXtProt AC: NX_Q96RQ3

  • Chr Location
    3q27; chr3:183015218-183099587 (-)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 10603
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed
  • HCOP
    human homology predictions: MCCC1
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human MCCC1 associations

Human Disease Mouse Models
       3-methylcrotonyl-Coa Carboxylase 1 Deficiency; MCC1D   OMIM: 210200
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    4 phenotype references
  • All Mutations and Alleles
    4
  • Gene trapped
    1
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    1 involving Mccc1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000029224 VEGA Gene Model | MGI Sequence Detail 41367 C57BL/6J ±  kb
transcript OTTMUST00000072440 VEGA | MGI Sequence Detail 2455 Not Applicable  
polypeptide OTTMUSP00000037295 VEGA | MGI Sequence Detail 717 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    467 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 17
    cDNA 16
    Primer pair 1

    Microarray probesets 5
Other
Accession IDs
less
MGI:1917422, MGI:2140108
References
more
  • Summaries
    All 38
    Developmental Gene Expression 2
    Gene Ontology 7
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/23/2016
MGI 6.05
The Jackson Laboratory