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Fundc1 Gene Detail
Summary
  • Symbol
    Fundc1
  • Name
    FUN14 domain containing 1
  • Synonyms
    1500005J14Rik, 1810033P05Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919268
    NCBI Gene: 72018
  • Gene Overview
    MyGene.info: FUNDC1
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    ChrX:17556564-17572325 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome X, 12.80 cM, cytoband A2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    45 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919268
protein coding gene ChrX:17519967-17572325 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035583
protein coding gene ChrX:12430862-12445266 (-)
A/J MGP_AJ_G0035560
protein coding gene ChrX:12532853-12550799 (-)
AKR/J MGP_AKRJ_G0035492
protein coding gene ChrX:12907326-12925542 (-)
BALB/cJ MGP_BALBcJ_G0035553
protein coding gene ChrX:12322740-12337283 (-)
C3H/HeJ MGP_C3HHeJ_G0035270
protein coding gene ChrX:12540473-12554942 (-)
C57BL/6NJ MGP_C57BL6NJ_G0036088
protein coding gene ChrX:12735353-12753174 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032953
protein coding gene ChrX:11034976-11050562 (-)
CAST/EiJ MGP_CASTEiJ_G0034562
protein coding gene ChrX:12094174-12109462 (-)
CBA/J MGP_CBAJ_G0035239
protein coding gene ChrX:13321385-13335814 (-)
DBA/2J MGP_DBA2J_G0035391
protein coding gene ChrX:12330404-12347578 (-)
FVB/NJ MGP_FVBNJ_G0035338
protein coding gene ChrX:12235795-12250410 (-)
LP/J MGP_LPJ_G0035473
protein coding gene ChrX:12747211-12761575 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035382
protein coding gene ChrX:13471520-13485919 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0036095
protein coding gene ChrX:12343312-12357641 (-)
PWK/PhJ MGP_PWKPhJ_G0034263
protein coding gene ChrX:11659250-11674449 (-)
SPRET/EiJ MGP_SPRETEiJ_G0034102
protein coding gene ChrX:12385049-12401970 (-)
WSB/EiJ MGP_WSBEiJ_G0034697
protein coding gene ChrX:12309295-12327479 (-)



Homology
more
  • Human Ortholog
    FUNDC1, FUN14 domain containing 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    FUNDC1, FUN14 domain containing 1
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 139341
    neXtProt AC: NX_Q8IVP5
    UniProt: Q8IVP5

  • Chr Location
    Xp11.3; chrX:44523639-44542975 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41738
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: FUNDC1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    5 phenotype references
No abnormal phenotype was observed in a high-throughput screen, nor in a pathology assessment.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000025040 Ensembl Gene Model | MGI Sequence Detail 15762 C57BL/6J ±  kb
transcript ENSMUST00000026016 Ensembl | MGI Sequence Detail 1983 Not Applicable  
polypeptide ENSMUSP00000026016 Ensembl | MGI Sequence Detail 155 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 70
    cDNA 70

    Microarray probesets 5
Other
Accession IDs
less
MGI:1916434
References
more
  • Summaries
    All 34
    Developmental Gene Expression 1
    Gene Ontology 9
    Phenotypes 5
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:239447 Zhang W, et al., Hypoxic mitophagy regulates mitochondrial quality and platelet activation and determines severity of I/R heart injury. Elife. 2016 Dec 20;5

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory