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Fndc3b
Gene Detail
Symbol

Name
ID
Fndc3b
fibronectin type III domain containing 3B
MGI:1919257
Synonyms
1600019O04Rik, fad104
Feature Type
protein coding gene
Genetic Map
Chromosome 3
10.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:27416162-27710439 bp, - strand
From NCBI annotation of GRCm38

  294278 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Fndc3b

Human
homologs
Human Homolog FNDC3B, fibronectin type III domain containing 3B
NCBI Gene ID 64778
neXtProt AC  NX_Q53EP0
Human Synonyms  FAD104, PRO4979, YVTM2421
Human Chr (Location)  3q26.31; chr3:172039628-172400703 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(130) : Gene trapped(125) Targeted(5)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a knock-out allele die shortly after birth despite normal energy homeostasis. Mouse embryonic fibroblasts homozygous for a knock-out allele exhibit impaired adipogenesis and enhanced osteogenesis.
 
Interactions
Fndc3b interacts with 453 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell migration, negative regulation of osteoblast differentiation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
Ensembl Gene ModelENSMUSG00000039286 (Evidence)
Entrez Gene72007 (Evidence)
DFCITC1575990, TC1757610
DoTSDT.101709471, DT.490892, DT.97408664
NIA Mouse Gene IndexU023900
Consensus CDS ProjectCCDS17274.1
International Mouse Knockout Project StatusFndc3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 72007 NCBI Gene Model | MGI Sequence Detail 294278 C57BL/6J ±  kb
transcript NM_173182 RefSeq | MGI Sequence Detail 6875 Not Specified 
polypeptide Q6NWW9 UniProt | EBI | MGI Sequence Detail 1207 Not Applicable 

For the selected sequences
All sequences(42) RefSeq(16) UniProt(1)
Polymorphisms
SNPs within 2kb(1899 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin, type III
InterPro IPR013783 Immunoglobulin-like fold
Protein Ontology PR:000007588 fibronectin type III domain-containing protein 3B
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204896 Kishimoto K, et al., FAD104, a regulatory factor of adipogenesis, acts as a novel regulator of calvarial bone formation. J Biol Chem. 2013 Nov 1;288(44):31772-83
All references(40)
Other
accession IDs
MGI:2140001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory