About   Help   FAQ
Fndc3b
Gene Detail
Symbol

Name
ID
Fndc3b
fibronectin type III domain containing 3B
MGI:1919257
Synonyms
1600019O04Rik, fad104
Feature Type
protein coding gene
Genetic Map
Chromosome 3
10.91 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr3:27416162-27711307 bp, - strand
From VEGA annotation of GRCm38

  295146 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:11244  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: FNDC3B
Gene Tree: Fndc3b

Human
homologs
FNDC3B, fibronectin type III domain containing 3B
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64778
neXtProt AC: NX_Q53EP0

Human Synonyms: FAD104, PRO4979, YVTM2421

Human Chr (Location): 3q26.31; chr3:172039628-172400703 (+)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(131) : Gene trapped(126) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
 
Mice homozygous for a knock-out allele die shortly after birth despite normal energy homeostasis. Mouse embryonic fibroblasts homozygous for a knock-out allele exhibit impaired adipogenesis and enhanced osteogenesis.
 
Interactions
Fndc3b interacts with 453 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process cell migration, negative regulation of osteoblast differentiation, ...
Component endoplasmic reticulum, integral component of membrane, ...
Function poly(A) RNA binding
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(13)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase fndc3b    NEW 
Molecular
reagents
All nucleic(13) cDNA(13)
Microarray probesets(4)
Other database
links
VEGA Gene Model OTTMUSG00000051189 (Evidence)
Ensembl Gene Model ENSMUSG00000039286 (Evidence)
Entrez Gene 72007 (Evidence)
DFCI TC1575990, TC1757610
DoTS DT.101709471, DT.490892, DT.97408664
NIA Mouse Gene Index U023900
Consensus CDS Project CCDS17274.1
International Mouse Phenotyping Consortium Status Fndc3b
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000051189 VEGA Gene Model | MGI Sequence Detail 295146 C57BL/6J ±  kb
transcript OTTMUST00000129644 VEGA | MGI Sequence Detail 6886 Not Applicable 
polypeptide OTTMUSP00000069618 VEGA | MGI Sequence Detail 1207 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(16) UniProt(2)
Polymorphisms
SNPs within 2kb(1900 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR003961 Fibronectin type III
InterPro IPR013783 Immunoglobulin-like fold
Protein Ontology PR:000007588 fibronectin type III domain-containing protein 3B
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:204896 Kishimoto K, et al., FAD104, a regulatory factor of adipogenesis, acts as a novel regulator of calvarial bone formation. J Biol Chem. 2013 Nov 1;288(44):31772-83
All references(41)
Other
accession IDs
MGI:2140001

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
08/25/2015
MGI 6.0
The Jackson Laboratory