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Sars2 Gene Detail
Summary
  • Symbol
    Sars2
  • Name
    seryl-aminoacyl-tRNA synthetase 2
  • Synonyms
    2410015F05Rik, D7Ertd353e
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919234
    NCBI Gene: 71984
  • Gene Overview
    MyGene.info: SARS2
Location & Maps
more
  • Sequence Map
    Chr7:28741992-28753871 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      11880 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 16.91 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    SARS2, seryl-tRNA synthetase 2, mitochondrial
  • Vertebrate Orthologs
    9
  • Human Ortholog
    SARS2, seryl-tRNA synthetase 2, mitochondrial
    Orthology source: HomoloGene, HGNC
  • Synonyms
    mtSerRS, SARS, SARSM, SerRS, SerRSmt, SERS, SYS
  • Links
    NCBI Gene ID: 54938
    neXtProt AC: NX_Q9NP81

  • Chr Location
    19q13.2; chr19:38915264-38930896 (-)  GRCh38.p2

Human Diseases
more
  • Diseases
    1 with human SARS2 associations

Human Disease Mouse Models
       Hyperuricemia, Pulmonary Hypertension, Renal Failure, and Alkalosis Syndrome; HUPRAS   OMIM: 613845
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotype references
  • All Mutations and Alleles
    5
  • Gene trapped
    3
  • Targeted
    2
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000059067 VEGA Gene Model | MGI Sequence Detail 11880 C57BL/6J ±  kb
transcript OTTMUST00000144899 VEGA | MGI Sequence Detail 1868 Not Applicable  
polypeptide OTTMUSP00000075497 VEGA | MGI Sequence Detail 518 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    127 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 49
    cDNA 48
    Primer pair 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:1196425
References
more
  • Summaries
    All 29
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/13/2016
MGI 6.05
The Jackson Laboratory