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Snx10
Gene Detail
Symbol

Name
ID
Snx10
sorting nexin 10
MGI:1919232
Synonyms
2410004M09Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 6
24.95 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr6:51523901-51590679 bp, + strand
From VEGA annotation of GRCm38

  66779 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32171  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: SNX10
Protein SuperFamily: sorting nexin, Snx3 type
Gene Tree: Snx10

Human
homologs
SNX10, sorting nexin 10
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 29887
neXtProt AC: NX_Q9Y5X0

Human Synonyms: OPTB8

Human Chr (Location): 7p15.2; chr7:26291895-26374383 (+)  GRCh38.p2

Disease Associations: (1) Diseases Associated with Human SNX10

Mutations,
alleles, and
phenotypes
All mutations/alleles(276) : Gene trapped(272) Targeted(4)
Incidental mutations (data from CvDC )
Interactions
Snx10 interacts with 207 markers (Mir1b, Mir7-1, Mir7-2, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (25 annotations)
Process cell projection organization, cilium assembly, ...
Component centrosome, cytoplasm, ...
Function 1-phosphatidylinositol binding, ATPase binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (3)    Tissues (2)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 1
RT-PCR 2
cDNA source data(123)
Other mouse links: Allen Institute   GEO   Expression Atlas
Other vertebrate links: Xenbase snx10 ; ZFIN snx10a    NEW 
Molecular
reagents
All nucleic(125) cDNA(123) Primer pair(2)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000023330 (Evidence)
Ensembl Gene Model ENSMUSG00000038301 (Evidence)
Entrez Gene 71982 (Evidence)
UniGene 294166
DFCI TC1592633, TC1572566
DoTS DT.101391370, DT.91553990, DT.534413, DT.94350354
NIA Mouse Gene Index U006862
Consensus CDS Project CCDS20136.1
International Mouse Phenotyping Consortium Status Snx10
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023330 VEGA Gene Model | MGI Sequence Detail 66779 C57BL/6J ±  kb
transcript OTTMUST00000056535 VEGA | MGI Sequence Detail 968 Not Applicable 
polypeptide OTTMUSP00000027183 VEGA | MGI Sequence Detail 201 Not Applicable 

For the selected sequences
All sequences(73) RefSeq(12) UniProt(8)
Polymorphisms
SNPs within 2kb(320 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
Protein Ontology PR:000015359 sorting nexin-10
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:183128 Zhu CH, et al., SNX10 is required for osteoclast formation and resorption activity. J Cell Biochem. 2012 May;113(5):1608-15
All references(34)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/28/2015
MGI 5.22
The Jackson Laboratory