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Utp3 Gene Detail
Summary
  • Symbol
    Utp3
  • Name
    UTP3 small subunit processome component
  • Synonyms
    2400011K09Rik, Crlz1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919230
    NCBI Gene: 65961
  • Alliance
    genome feature page
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:88702321-88703949 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 5, 43.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    89 from dbSNP Build 142
  • Strain Annotations
    19
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919230
 protein coding gene Chr5:88702321-88703949 (+)
129S1/SvImJ ENSMUSG00200007576
 protein coding gene Chr5:84430950-84432578 (+)
A/J ENSMUSG00195025098
 protein coding gene Chr5:83603989-83605617 (+)
AKR/J ENSMUSG00220010768
 protein coding gene Chr5:83747068-83748696 (+)
BALB/cJ ENSMUSG00180023701
 protein coding gene Chr5:83430711-83432339 (+)
C3H/HeJ ENSMUSG00175039165
 protein coding gene Chr5:85522519-85524147 (+)
C57BL/6NJ ENSMUSG00215028499
 protein coding gene Chr5:84296812-84298440 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0027375
 protein coding gene Chr5:81830860-81832505 (+)
CAST/EiJ ENSTCUG00005032949
 protein coding gene Chr5:83240269-83241901 (+)
CBA/J ENSMUSG00210005817
 protein coding gene Chr5:84325922-84327550 (+)
DBA/2J ENSMUSG00185038588
 protein coding gene Chr5:86240338-86241966 (+)
FVB/NJ ENSMUSG00205018431
 protein coding gene Chr5:83141068-83142696 (+)
JF1/MsJ ENSUMUG00000000495
 protein coding gene Chr5:90604629-90606261 (+)
LP/J ENSMUSG00230001193
 protein coding gene Chr5:90957458-90959086 (+)
NOD/ShiLtJ ENSMUSG00190027625
 protein coding gene Chr5:83194244-83195872 (+)
NZO/HlLtJ ENSMUSG00225007995
 protein coding gene Chr5:96106536-96108164 (+)
PWK/PhJ ENSLUMG00010028209
 protein coding gene Chr5:83266630-83268262 (+)
SPRET/EiJ ENSMSPG00010034943
 protein coding gene Chr5:85676011-85677641 (+)
WSB/EiJ ENSIUOG00005025992
 protein coding gene Chr5:86223066-86224694 (+)



Homology
more
  • Human Ortholog
    UTP3, UTP3 small subunit processome component
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    UTP3, UTP3 small subunit processome component
  • Synonyms
    CRL1, CRLZ1, SAS10
  • Links
    NCBI Gene ID: 57050
    UniProt: Q9NQZ2

  • Chr Location
    4q13.3; chr4:70688532-70690551 (+)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    10
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    2
  • Gene trapped
    3
  • Radiation induced
    1
  • Spontaneous
    1
  • Targeted
    1
  • Genomic Mutations
    4 involving Utp3
  • Incidental Mutations
    APF
  • Find Mice (IMSR)
    10 strains or lines available
Mice homozygous for a null allele exhibit prenatal lethality associated with reduced embryo size and a failure to develop a body shape.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    15
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
membraneless organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    619
  • Tissues
    19
  • cDNA Data
    11
  • Literature Summary
    1
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 65961 NCBI Gene Model | MGI Sequence Detail 1629 C57BL/6J ±  kb
transcript NM_023054 RefSeq | MGI Sequence Detail 1646 C57BL/6  
polypeptide Q9JI13 UniProt | EBI | MGI Sequence Detail 469 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 11
    cDNA 11

    Microarray probesets 5
Other
Accession IDs
less
MGI:2141238, MGI:2141343
References
more
  • Summaries
    All 41
    Developmental Gene Expression 1
    Gene Ontology 7
    Phenotypes 10
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:327317 Choi SY, et al., Crlz-1 Homozygous Null Knockout Mouse Embryos Are Lethally Stopped in Their Early Development. Genes (Basel). 2022 Mar 14;13(3)
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
09/01/2026
MGI 6.24 		The Jackson Laboratory