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Ppp2r2a Gene Detail
Summary
  • Symbol
    Ppp2r2a
  • Name
    protein phosphatase 2, regulatory subunit B, alpha
  • Synonyms
    2410004D02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919228
    NCBI Gene: 71978
  • Gene Overview
    MyGene.info: PPP2R2A
Location & Maps
more
  • Sequence Map
    Chr14:67014057-67072471 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      58415 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 14, 34.60 cM, cytoband D1
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    PPP2R2A, protein phosphatase 2 regulatory subunit Balpha
  • Vertebrate Orthologs
    9
  • Human Ortholog
    PPP2R2A, protein phosphatase 2 regulatory subunit Balpha
    Orthology source: HGNC, HomoloGene
  • Synonyms
    B55A, B55ALPHA, PR52A, PR55A
  • Links
    NCBI Gene ID: 5520
    neXtProt AC: NX_P63151

  • Chr Location
    8p21.2; chr8:26291491-26372680 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    11 phenotype references
  • All Mutations and Alleles
    43
  • Chemically induced (other)
    1
  • Gene trapped
    37
  • Targeted
    5
  • Genomic Mutations
    1 involving Ppp2r2a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022052 Ensembl Gene Model | MGI Sequence Detail 58415 C57BL/6J ±  kb
transcript ENSMUST00000089230 Ensembl | MGI Sequence Detail 4036 Not Applicable  
polypeptide ENSMUSP00000086640 Ensembl | MGI Sequence Detail 447 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    281 from dbSNP Build 142
Protein
Information
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  • UniProt
    6 Sequences
  • Protein Ontology
    PR:000003213 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
  • InterPro Domains
    IPR000009 Protein phosphatase 2A regulatory subunit PR55
    IPR018067 Protein phosphatase 2A regulatory subunit PR55, conserved site
    IPR001680 WD40 repeat
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
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  • All nucleic 152
    cDNA 150
    Primer pair 2

    Microarray probesets 7
References
more
  • Summaries
    All 36
    Developmental Gene Expression 4
    Gene Ontology 4
    Phenotypes 11
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:199582 Youssef G, et al., Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory