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Ppp2r2a
Gene Detail
 Symbol
Name
ID
Ppp2r2a
protein phosphatase 2, regulatory subunit B, alpha
MGI:1919228
Synonyms 2410004D02Rik
Feature Type protein coding gene
Genetic Map
Chromosome 14
34.60 cM, cytoband D1
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr14:67014057-67072471 bp, - strand
From Ensembl annotation of GRCm38

  58415 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:2035  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: serine/threonine-protein phosphatase 2A, subunit B55
Gene Tree: Ppp2r2a

Human
homologs
Human Homolog PPP2R2A, protein phosphatase 2, regulatory subunit B, alpha
NCBI Gene ID 5520
neXtProt AC  NX_P63151
Human Synonyms  B55A, B55ALPHA, PR52A, PR55A
Human Chr (Location)  8p21.2; chr8:26291491-26372680 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(41) : Gene trapped(37) Targeted(4)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ppp2r2a interacts with 367 markers (Mir1a-1, Mir1a-2, Mir7-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process protein dephosphorylation, response to morphine, ...
Component protein phosphatase type 2A complex
Function protein complex binding, protein phosphatase 2A binding, ...
External Resources: FuncBase
Expression
Literature Summary: (4 records)
Data Summary: Results (22)    Tissues (14)    Images (3)
Theiler Stages: 17, 20, 23, 28
Assay TypeResults
Immunohistochemistry 4
RNA in situ 6
Western blot 4
RT-PCR 8
cDNA source data(150)
External Resources: Allen Institute   GENSAT   GEO   Expression Atlas
Molecular
reagents
All nucleic(152) cDNA(150) Primer pair(2)
Microarray probesets(7)
Other database
links
Ensembl Gene ModelENSMUSG00000022052 (Evidence)
Entrez Gene71978 (Evidence)
UniGene273997
DFCITC1572718, TC1631087, TC1650142
DoTSDT.101351720, DT.101394544, DT.101737180, DT.55138875, DT.55228319
NIA Mouse Gene IndexU035710, U118667
Consensus CDS ProjectCCDS56967.1
International Mouse Knockout Project StatusPpp2r2a
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000022052 Ensembl Gene Model | MGI Sequence Detail 58415 C57BL/6J ±  kb
transcript ENSMUST00000089230 Ensembl | MGI Sequence Detail 4036 Not Applicable 
polypeptide ENSMUSP00000086640 Ensembl | MGI Sequence Detail 447 Not Applicable 

For the selected sequences
All sequences(46) RefSeq(6) UniProt(6)
Polymorphisms SNPs within 2kb(283 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000009 Protein phosphatase 2A, regulatory subunit PR55
InterPro IPR018067 Protein phosphatase 2A, regulatory subunit PR55, conserved site
InterPro IPR001680 WD40 repeat
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000003213 serine/threonine-protein phosphatase 2A 55 kDa regulatory subunit B alpha isoform
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:199582 Youssef G, et al., Rab3Gap1 mediates exocytosis of Claudin-1 and tight junction formation during epidermal barrier acquisition. Dev Biol. 2013 Aug 15;380(2):274-85
All references(40)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory