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Zdhhc13 Gene Detail
Summary
  • Symbol
    Zdhhc13
  • Name
    zinc finger, DHHC domain containing 13
  • Synonyms
    2410004E01Rik, Hip14l, kojak, skc4
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919227
    NCBI Gene: 243983
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:48789003-48827437 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 7, 31.11 cM, cytoband B3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    320 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919227
protein coding gene Chr7:48789003-48827440 (.)
129S1/SvImJ MGP_129S1SvImJ_G0032294
protein coding gene Chr7:49392154-49432451 (+)
A/J MGP_AJ_G0032273
protein coding gene Chr7:48700283-48738719 (+)
AKR/J MGP_AKRJ_G0032209
protein coding gene Chr7:49842802-49882585 (+)
BALB/cJ MGP_BALBcJ_G0032285
protein coding gene Chr7:48347831-48386521 (+)
C3H/HeJ MGP_C3HHeJ_G0031998
protein coding gene Chr7:50216708-50256581 (+)
C57BL/6NJ MGP_C57BL6NJ_G0032778
protein coding gene Chr7:51699171-51738132 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0029784
protein coding gene Chr7:51875868-51914148 (+)
CAST/EiJ MGP_CASTEiJ_G0031326
protein coding gene Chr7:41599522-41637925 (+)
CBA/J MGP_CBAJ_G0031963
protein coding gene Chr7:53432203-53475327 (+)
DBA/2J MGP_DBA2J_G0032120
protein coding gene Chr7:47910689-47948915 (+)
FVB/NJ MGP_FVBNJ_G0032074
protein coding gene Chr7:47837467-47875624 (+)
LP/J MGP_LPJ_G0032201
protein coding gene Chr7:50354237-50393687 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0032111
protein coding gene Chr7:52555560-52594708 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0032795
protein coding gene Chr7:48821908-48861136 (+)
PWK/PhJ MGP_PWKPhJ_G0031046
protein coding gene Chr7:41242598-41283810 (+)
SPRET/EiJ MGP_SPRETEiJ_G0030887
protein coding gene Chr7:36992327-37031918 (+)
WSB/EiJ MGP_WSBEiJ_G0031444
protein coding gene Chr7:49479899-49518242 (+)



Homology
more
  • Human Ortholog
    ZDHHC13, zinc finger DHHC-type containing 13
  • Vertebrate Orthologs
    9
  • Human Ortholog
    ZDHHC13, zinc finger DHHC-type containing 13
    Orthology source: HGNC, HomoloGene
  • Synonyms
    HIP14L, HIP3RP
  • Links
    NCBI Gene ID: 54503
    neXtProt AC: NX_Q8IUH4
    UniProt: Q8IUH4

  • Chr Location
    11p15.1; chr11:19117099-19176420 (+)  GRCh38.p7

Human Diseases
more
  • Diseases
    1 with Zdhhc13 mouse models

Human Disease Mouse Models
      
IDs
View 1 model
Click on a disease name to see all genes associated with that disease.

  • Mutations/Alleles
    1 with disease annotations
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    50 phenotypes from 2 alleles in 4 genetic backgrounds
    6 images
    14 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU mutation display wasting, weight loss, hair loss (alopecia), reduced bone mineral density (osteoporosis), and generalized amyloid deposition, which resulted in early death.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 243983 NCBI Gene Model | MGI Sequence Detail 38435 C57BL/6J ±  kb
    transcript NM_028031 RefSeq | MGI Sequence Detail 2407 C57BL/6  
    polypeptide Q9CWU2 UniProt | EBI | MGI Sequence Detail 622 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 40
      cDNA 38
      Primer pair 2

      Microarray probesets 3
    Other
    Accession IDs
    less
    MGI:2671602
    References
    more
    • Summaries
      All 45
      Developmental Gene Expression 7
      Diseases 1
      Gene Ontology 6
      Phenotypes 14
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:257304 Shen LF, et al., Role of S-Palmitoylation by ZDHHC13 in Mitochondrial function and Metabolism in Liver. Sci Rep. 2017 May 19;7(1):2182

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    12/04/2018
    MGI 6.13
    The Jackson Laboratory