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Fam53a Gene Detail
Summary
  • Symbol
    Fam53a
  • Name
    family with sequence similarity 53, member A
  • Synonyms
    2410018C17Rik, 5430419M09Rik, DNTNP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919225
    NCBI Gene: 74504
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:33600347-33629635 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 17.83 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    251 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919225
protein coding gene Chr5:33600347-33629675 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029447
protein coding gene Chr5:31783352-31812603 (-)
A/J MGP_AJ_G0029414
protein coding gene Chr5:30752398-30781709 (-)
AKR/J MGP_AKRJ_G0029363
protein coding gene Chr5:31937090-31967203 (-)
BALB/cJ MGP_BALBcJ_G0029424
protein coding gene Chr5:31281193-31310894 (-)
C3H/HeJ MGP_C3HHeJ_G0029146
protein coding gene Chr5:31975388-32006946 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029878
protein coding gene Chr5:33664673-33695037 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027115
protein coding gene Chr5:28552882-28582684 (-)
CAST/EiJ MGP_CASTEiJ_G0028555
protein coding gene Chr5:31057173-31086992 (-)
CBA/J MGP_CBAJ_G0029114
protein coding gene Chr5:34378969-34413619 (-)
DBA/2J MGP_DBA2J_G0029262
protein coding gene Chr5:30930146-30960293 (-)
FVB/NJ MGP_FVBNJ_G0029221
protein coding gene Chr5:30356526-30385918 (-)
LP/J MGP_LPJ_G0029347
protein coding gene Chr5:32206297-32236275 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029251
protein coding gene Chr5:35237579-35267654 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029911
protein coding gene Chr5:31447059-31478661 (-)
PWK/PhJ MGP_PWKPhJ_G0028280
protein coding gene Chr5:30059849-30088945 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028111
protein coding gene Chr5:30905979-30935975 (-)
WSB/EiJ MGP_WSBEiJ_G0028636
protein coding gene Chr5:31511792-31543924 (-)



Homology
more
  • Human Ortholog
    FAM53A, family with sequence similarity 53 member A
  • Vertebrate Orthologs
    7
  • Human Ortholog
    FAM53A, family with sequence similarity 53 member A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DNTNP
  • Links
    NCBI Gene ID: 152877
    neXtProt AC: NX_Q6NSI3
    UniProt: Q6NSI3

  • Chr Location
    4p16.3; chr4:1574055-1684313 (-)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    29 phenotype references
  • All Mutations and Alleles
    39
  • Chemically induced (ENU)
    1
  • Chemically induced (other)
    2
  • Endonuclease-mediated
    1
  • Gene trapped
    29
  • Radiation induced
    3
  • Spontaneous
    1
  • Targeted
    2
  • Genomic Mutations
    7 involving Fam53a
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037339 Ensembl Gene Model | MGI Sequence Detail 29289 C57BL/6J ±  kb
transcript ENSMUST00000065119 Ensembl | MGI Sequence Detail 2009 Not Applicable  
polypeptide ENSMUSP00000070770 Ensembl | MGI Sequence Detail 402 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 46
    cDNA 46

    Microarray probesets 3
Other
Accession IDs
less
MGI:1921754
References
more
  • Summaries
    All 53
    Developmental Gene Expression 3
    Diseases 1
    Gene Ontology 2
    Phenotypes 29
  • Earliest
    J:5021 Batchelor AL, et al., A comparison of the mutagenic effectiveness of chronic neutron- and gamma-irradiation of mouse spermatogonia. Mutat Res. 1966 Jun;3(3):218-29
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
12/03/2019
MGI 6.14
The Jackson Laboratory