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Prmt3
Gene Detail
 Symbol
Name
ID
Prmt3
protein arginine N-methyltransferase 3
MGI:1919224
Synonyms 2010005E20Rik, 2410018A17Rik, Hrmt1l3
Feature Type protein coding gene
Genetic Map
Chromosome 7
31.44 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr7:49778346-49858265 bp, + strand
From VEGA annotation of GRCm38

  79920 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:24255  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Protein SuperFamily: type 1 arginine N-methyltransferase
Gene Tree: Prmt3

Human
homologs
Human Homolog PRMT3, protein arginine methyltransferase 3
NCBI Gene ID 10196
neXtProt AC  NX_O60678
Human Synonyms  HRMT1L3
Human Chr (Location)  11p15.1; chr11:20387530-20509333 (+)  GRCh38
Alleles
and
phenotypes
All alleles(11) : Gene trapped(9) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for a hypomorphic gene trap allele exhibit a reduced embryonic size but survive birth and attain a normal size in adulthood.
 
Gene Ontology
(GO)
classifications
All GO classifications: (83 annotations)
Process histone arginine methylation, methylation, ...
Component cytoplasm, cytosol, ...
Function 1-hydroxy-6-methoxypyrene methyltransferase activity, 1-hydroxypyrene methyltransferase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (51)    Tissues (43)    Images (12)
Theiler Stages: 19, 21, 23, 28
Assay TypeResults
RNA in situ 49
RT-PCR 2
cDNA source data(9)
External Resources: Allen Institute   GEO   ArrayExpress
Molecular
reagents
All nucleic(10) cDNA(9) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000020564 (Evidence)
Ensembl Gene ModelENSMUSG00000030505 (Evidence)
Entrez Gene71974 (Evidence)
DFCITC1576193, TC1590176, TC1762689
DoTSDT.40178630, DT.532924, DT.55156409
NIA Mouse Gene IndexU008129, U062227
EC2.1.1.-
PDB1WIR
Consensus CDS ProjectCCDS21307.1
International Mouse Knockout Project StatusPrmt3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000020564 VEGA Gene Model | MGI Sequence Detail 79920 C57BL/6J ±  kb
transcript OTTMUST00000048733 VEGA | MGI Sequence Detail 2507 Not Applicable 
polypeptide OTTMUSP00000022425 VEGA | MGI Sequence Detail 528 Not Applicable 

For the selected sequences
All sequences(66) RefSeq(6) UniProt(7)
Polymorphisms SNPs within 2kb(591 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR025799 Protein arginine N-methyltransferase
InterPro IPR010456 Ribosomal L11 methyltransferase, PrmA
InterPro IPR015880 Zinc finger, C2H2-like
Protein Ontology PR:000013254 protein arginine N-methyltransferase 3
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:203762 Burton A, et al., Single-cell profiling of epigenetic modifiers identifies PRDM14 as an inducer of cell fate in the mammalian embryo. Cell Rep. 2013 Nov 14;5(3):687-701
All references(48)
Other
accession IDs
MGI:1917085, MGI:2142102

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/15/2014
MGI 5.18
The Jackson Laboratory