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Wdr73 Gene Detail
Summary
  • Symbol
    Wdr73
  • Name
    WD repeat domain 73
  • Synonyms
    1200011I23Rik, 2410008B13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919218
    NCBI Gene: 71968
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr7:80540471-80551017 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 7, 45.71 cM, cytoband D2
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    83 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919218
protein coding gene Chr7:80540471-80551017 (-)
129S1/SvImJ MGP_129S1SvImJ_G0032420
protein coding gene Chr7:82900684-82911228 (-)
A/J MGP_AJ_G0032399
protein coding gene Chr7:80953021-80963578 (-)
AKR/J MGP_AKRJ_G0032335
protein coding gene Chr7:82720876-82731431 (-)
BALB/cJ MGP_BALBcJ_G0032411
protein coding gene Chr7:80622422-80633233 (-)
C3H/HeJ MGP_C3HHeJ_G0032124
protein coding gene Chr7:83361177-83371721 (-)
C57BL/6NJ MGP_C57BL6NJ_G0032903
protein coding gene Chr7:86148377-86158893 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0029911
protein coding gene Chr7:83459382-83469791 (-)
CAST/EiJ MGP_CASTEiJ_G0031452
protein coding gene Chr7:74264782-74275358 (-)
CBA/J MGP_CBAJ_G0032090
protein coding gene Chr7:89015527-89028935 (-)
DBA/2J MGP_DBA2J_G0032245
protein coding gene Chr7:79500094-79510638 (-)
FVB/NJ MGP_FVBNJ_G0032200
protein coding gene Chr7:79434584-79445137 (-)
LP/J MGP_LPJ_G0032326
protein coding gene Chr7:84141355-84151923 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0032237
protein coding gene Chr7:89140523-89151275 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0032921
protein coding gene Chr7:82157159-82167621 (-)
PWK/PhJ MGP_PWKPhJ_G0031172
protein coding gene Chr7:72704929-72715287 (-)
SPRET/EiJ MGP_SPRETEiJ_G0031013
protein coding gene Chr7:69174770-69185146 (-)
WSB/EiJ MGP_WSBEiJ_G0031570
protein coding gene Chr7:82515398-82526067 (-)



Homology
more
  • Human Ortholog
    WDR73, WD repeat domain 73
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    WDR73, WD repeat domain 73
  • Synonyms
    GAMOS, GAMOS1, HSPC264
  • Links
    NCBI Gene ID: 84942
    neXtProt AC: NX_Q6P4I2
    UniProt: Q6P4I2

  • Chr Location
    15q25.2; chr15:84639285-84654343 (-)  GRCh38

Human Diseases
more
  • Diseases
    1 with human WDR73 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    21 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

No experimental evidence to support Molecular Function annotation, following literature review. See J:73796.
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
  • Comparison Matrix
  • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71968 NCBI Gene Model | MGI Sequence Detail 10547 C57BL/6J ±  kb
    transcript NR_027976 RefSeq | MGI Sequence Detail 2587 C57BL/6  
    polypeptide Q9CWR1 UniProt | EBI | MGI Sequence Detail 371 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 65
      Genomic 1
      cDNA 64

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:1921389, MGI:2142049, MGI:2142355
    References
    more
    • Summaries
      All 47
      Gene Ontology 3
      Phenotypes 21
    • Earliest
      J:88307 Giometti CS, et al., The analysis of recessive lethal mutations in mice by using two-dimensional gel electrophoresis of liver proteins. Mutat Res. 1990 Sep;242(1):47-55
    • Latest
      J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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    last database update
    03/12/2024
    MGI 6.23
    The Jackson Laboratory