Nkiras2
Gene Detail

Symbol Name ID

Nkiras2 NFKB inhibitor interacting Ras-like protein 2 MGI:1919216

Synonyms

2410003M04Rik, 4930527H08Rik, KBRAS2

Feature Type

protein coding gene

Genetic Map

Chromosome 11

63.47 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr11:100619244-100627607 bp, + strand From VEGA annotation of GRCm38   8364 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:9738  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 2 zebrafish

Protein SuperFamily: Ras-related protein Rab
Gene Tree: Nkiras2

Human homologs

Human Homolog		NKIRAS2, NFKB inhibitor interacting Ras-like 2
NCBI Gene ID		28511
neXtProt AC		NX_Q9NYR9
Human Synonyms		kappaB-Ras2, KBRAS2
Human Chr (Location)		17q21.2; chr17:40169594-40177659 (+)  GRCh37.p10

Alleles and phenotypes

All alleles(19) : Targeted(2) Gene trapped(17)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	GTP catabolic process, signal transduction, ...
Component	cytoplasm, membrane
Function	GTPase activity, GTP binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (16)    Tissues (6)    Images (9)
Theiler Stages: 22, 23

Assay Type	Results
RNA in situ	16

cDNA source data(12)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(14) cDNA(14)
Microarray probesets(3)

Other database links

VEGA Gene Model	OTTMUSG00000002025 (Evidence)
Ensembl Gene Model	ENSMUSG00000017837 (Evidence)
Entrez Gene	71966 (Evidence)
DFCI	TC1572015
NIA Mouse Gene Index	U013343
Consensus CDS Project	CCDS25429.1
International Mouse Knockout Project Status	Nkiras2

Sequences

Length	Strain/Species
genomic	OTTMUSG00000002025	VEGA Gene Model | MGI Sequence Detail	8364	C57BL/6J
transcript	OTTMUST00000004105	VEGA | MGI Sequence Detail	2097	Not Applicable
polypeptide	OTTMUSP00000001970	VEGA | MGI Sequence Detail	191	Not Applicable

All sequences(51) RefSeq(2) UniProt(2)

Polymorphisms

SNPs(49 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR001806	Small GTPase superfamily
InterPro	IPR020849	Small GTPase superfamily, Ras type
InterPro	IPR005225	Small GTP-binding protein domain
Protein Ontology	PR:000011236	NF-kappa-B inhibitor-interacting Ras-like protein 2

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(36)

Other accession IDs

MGI:1922407