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Cdca4 Gene Detail
Summary
  • Symbol
    Cdca4
  • Name
    cell division cycle associated 4
  • Synonyms
    2410018C03Rik, Hepp, SEI-3
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919213
    NCBI Gene: 71963
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr12:112820229-112829423 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 12, 61.20 cM, cytoband F2
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    110 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919213
protein coding gene Chr12:112820229-112829516 (-)
129S1/SvImJ MGP_129S1SvImJ_G0020162
protein coding gene Chr12:115290039-115299191 (-)
A/J MGP_AJ_G0020118
protein coding gene Chr12:110842863-110851958 (-)
AKR/J MGP_AKRJ_G0020093
protein coding gene Chr12:114045432-114054527 (-)
BALB/cJ MGP_BALBcJ_G0020103
protein coding gene Chr12:111290219-111299371 (-)
C3H/HeJ MGP_C3HHeJ_G0019905
protein coding gene Chr12:114557791-114566886 (-)
C57BL/6NJ MGP_C57BL6NJ_G0020548
protein coding gene Chr12:118858458-118867610 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0018162
protein coding gene Chr12:107276329-107285800 (-)
CAST/EiJ MGP_CASTEiJ_G0019445
protein coding gene Chr12:109399238-109410390 (-)
CBA/J MGP_CBAJ_G0019872
protein coding gene Chr12:123395679-123404774 (-)
DBA/2J MGP_DBA2J_G0019989
protein coding gene Chr12:110329381-110338533 (-)
FVB/NJ MGP_FVBNJ_G0019974
protein coding gene Chr12:109165268-109174572 (-)
LP/J MGP_LPJ_G0020063
protein coding gene Chr12:115118816-115128972 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0020012
protein coding gene Chr12:126484272-126493424 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0020577
protein coding gene Chr12:113573468-113582565 (-)
PWK/PhJ MGP_PWKPhJ_G0019207
protein coding gene Chr12:104986243-104995337 (-)
SPRET/EiJ MGP_SPRETEiJ_G0019011
protein coding gene Chr12:107744385-107753650 (-)
WSB/EiJ MGP_WSBEiJ_G0019505
protein coding gene Chr12:114483643-114492736 (-)



Homology
more
  • Human Ortholog
    CDCA4, cell division cycle associated 4
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDCA4, cell division cycle associated 4
    Orthology source: HomoloGene, HGNC
  • Synonyms
    HEPP, SEI-3/HEPP
  • Links
    NCBI Gene ID: 55038
    neXtProt AC: NX_Q9BXL8
    UniProt: Q9BXL8

  • Chr Location
    14q32.33; chr14:105009573-105021088 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9936
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CDCA4
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047832 Ensembl Gene Model | MGI Sequence Detail 9195 C57BL/6J ±  kb
transcript ENSMUST00000062092 Ensembl | MGI Sequence Detail 2425 Not Applicable  
polypeptide ENSMUSP00000058901 Ensembl | MGI Sequence Detail 237 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 89
    cDNA 88
    Other 1

    Microarray probesets 4
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:211498 Peng Y, et al., Sertad1 encodes a novel transcriptional co-activator of SMAD1 in mouse embryonic hearts. Biochem Biophys Res Commun. 2013 Nov 29;441(4):751-6

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory