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Ints11 Gene Detail
Summary
  • Symbol
    Ints11
  • Name
    integrator complex subunit 11
  • Synonyms
    2410006F12Rik, Cpsf3l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919207
    NCBI Gene: 71957
  • Gene Overview
    MyGene.info: INTS11
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:155869547-155889103 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 87.66 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    307 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919207
protein coding gene Chr4:155869546-155889103 (.)
129S1/SvImJ MGP_129S1SvImJ_G0029236
protein coding gene Chr4:160240006-160261890 (+)
A/J MGP_AJ_G0029201
protein coding gene Chr4:153487882-153508318 (+)
AKR/J MGP_AKRJ_G0029149
protein coding gene Chr4:157666651-157686329 (+)
BALB/cJ MGP_BALBcJ_G0029217
protein coding gene Chr4:153961574-153981439 (+)
C3H/HeJ MGP_C3HHeJ_G0028938
protein coding gene Chr4:158209282-158229043 (+)
C57BL/6NJ MGP_C57BL6NJ_G0029666
protein coding gene Chr4:165916948-165939423 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0026910
protein coding gene Chr4:145776364-145795322 (+)
CAST/EiJ MGP_CASTEiJ_G0028350
protein coding gene Chr4:155680788-155699892 (+)
CBA/J MGP_CBAJ_G0028900
protein coding gene Chr4:170931765-170956072 (+)
DBA/2J MGP_DBA2J_G0029049
protein coding gene Chr4:153508729-153529511 (+)
FVB/NJ MGP_FVBNJ_G0029012
protein coding gene Chr4:152758053-152780137 (+)
LP/J MGP_LPJ_G0029139
protein coding gene Chr4:160167453-160191666 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0029039
protein coding gene Chr4:173745470-173765497 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0029698
protein coding gene Chr4:158292705-158318965 (+)
PWK/PhJ MGP_PWKPhJ_G0028071
protein coding gene Chr4:149652255-149672464 (+)
SPRET/EiJ MGP_SPRETEiJ_G0027905
protein coding gene Chr4:152551900-152574785 (+)
WSB/EiJ MGP_WSBEiJ_G0028430
protein coding gene Chr4:158466726-158489220 (+)



Homology
more
  • Human Ortholog
    INTS11, integrator complex subunit 11
  • Vertebrate Orthologs
    10
  • Human Ortholog
    INTS11, integrator complex subunit 11
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CPSF3L, CPSF73L, INT11, RC68, RC-68
  • Links
    NCBI Gene ID: 54973
    neXtProt AC: NX_Q5TA45
    UniProt: Q5TA45

  • Chr Location
    1p36.33; chr1:1311585-1324687 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 9894
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: INTS11
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71957 NCBI Gene Model | MGI Sequence Detail 19557 C57BL/6J ±  kb
transcript NM_028020 RefSeq | MGI Sequence Detail 2347 C57BL/6  
polypeptide Q9CWS4 UniProt | EBI | MGI Sequence Detail 600 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 91
    Genomic 1
    cDNA 90

    Microarray probesets 2
Other
Accession IDs
less
MGI:2140491
References
more
  • Summaries
    All 33
    Developmental Gene Expression 1
    Gene Ontology 4
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:229253 Spies N, et al., Constraint and divergence of global gene expression in the mammalian embryo. Elife. 2015;4:e05538

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory