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Ephx3 Gene Detail
Summary
  • Symbol
    Ephx3
  • Name
    epoxide hydrolase 3
  • Synonyms
    2310063B19Rik, Abhd9
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919182
    NCBI Gene: 71932
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr17:32183770-32189549 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 17, 17.39 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    70 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919182
protein coding gene Chr17:32183770-32189848 (-)
129S1/SvImJ MGP_129S1SvImJ_G0023499
protein coding gene Chr17:32007149-32017721 (-)
A/J MGP_AJ_G0023456
protein coding gene Chr17:30952932-30958536 (-)
AKR/J MGP_AKRJ_G0023422
protein coding gene Chr17:31242735-31248143 (-)
BALB/cJ MGP_BALBcJ_G0023461
protein coding gene Chr17:31046917-31052528 (-)
C3H/HeJ MGP_C3HHeJ_G0023223
protein coding gene Chr17:31628779-31634864 (-)
C57BL/6NJ MGP_C57BL6NJ_G0023904
protein coding gene Chr17:33101950-33107446 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0021378
protein coding gene Chr17:28055625-28061233 (-)
CAST/EiJ MGP_CASTEiJ_G0022724
protein coding gene Chr17:31668551-31674264 (-)
CBA/J MGP_CBAJ_G0023198
protein coding gene Chr17:34534360-34543981 (-)
DBA/2J MGP_DBA2J_G0023328
protein coding gene Chr17:30328598-30334214 (-)
FVB/NJ MGP_FVBNJ_G0023298
protein coding gene Chr17:30155105-30160450 (-)
LP/J MGP_LPJ_G0023406
protein coding gene Chr17:32226772-32235293 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0023316
protein coding gene Chr17:33619716-33627183 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0023946
protein coding gene Chr17:31590377-31595764 (-)
PWK/PhJ MGP_PWKPhJ_G0022473
protein coding gene Chr17:29221278-29226892 (-)
SPRET/EiJ MGP_SPRETEiJ_G0022292
protein coding gene Chr17:29610443-29615869 (-)
WSB/EiJ MGP_WSBEiJ_G0022786
protein coding gene Chr17:31574890-31581749 (-)



Homology
more
  • Human Ortholog
    EPHX3, epoxide hydrolase 3
  • Vertebrate Orthologs
    5
  • Human Ortholog
    EPHX3, epoxide hydrolase 3
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ABHD9, EH3
  • Links
    NCBI Gene ID: 79852
    neXtProt AC: NX_Q9H6B9
    UniProt: Q9H6B9

  • Chr Location
    19p13.12; chr19:15226919-15233047 (-)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    7 phenotype references
Mice homozygous for a null allele are viable and fertile with no gross abnormalities.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000037577 Ensembl Gene Model | MGI Sequence Detail 5780 C57BL/6J ±  kb
transcript ENSMUST00000087721 Ensembl | MGI Sequence Detail 2416 Not Applicable  
polypeptide ENSMUSP00000085013 Ensembl | MGI Sequence Detail 424 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 6
    cDNA 6

    Microarray probesets 2
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:246524 Hoopes SL, et al., Generation and characterization of epoxide hydrolase 3 (EPHX3)-deficient mice. PLoS One. 2017;12(4):e0175348

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory