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Bdh1 Gene Detail
Summary
  • Symbol
    Bdh1
  • Name
    3-hydroxybutyrate dehydrogenase, type 1
  • Synonyms
    2310032J20Rik, Bdh
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919161
    NCBI Gene: 71911
  • Gene Overview
    MyGene.info: BDH1
  • Alliance
    gene page
  • Transcription Start Sites
    11 TSS
Location &
Maps
more
  • Sequence Map
    Chr16:31422297-31458901 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 16, 21.74 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    296 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919161
 protein coding gene Chr16:31422280-31458901 (+)
129S1/SvImJ MGP_129S1SvImJ_G0022720
 protein coding gene Chr16:29390830-29440436 (+)
A/J MGP_AJ_G0022685
 protein coding gene Chr16:28046056-28083731 (+)
AKR/J MGP_AKRJ_G0022658
 protein coding gene Chr16:29092852-29130536 (+)
BALB/cJ MGP_BALBcJ_G0022687
 protein coding gene Chr16:28200742-28237740 (+)
C3H/HeJ MGP_C3HHeJ_G0022452
 protein coding gene Chr16:29195004-29237055 (+)
C57BL/6NJ MGP_C57BL6NJ_G0023136
 protein coding gene Chr16:30020219-30065485 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0020654
 protein coding gene Chr16:28428684-28464598 (+)
CAST/EiJ MGP_CASTEiJ_G0021980
 protein coding gene Chr16:29302433-29338658 (+)
CBA/J MGP_CBAJ_G0022422
 protein coding gene Chr16:31276215-31329467 (+)
DBA/2J MGP_DBA2J_G0022555
 protein coding gene Chr16:27902076-27941155 (+)
FVB/NJ MGP_FVBNJ_G0022530
 protein coding gene Chr16:27877578-27914048 (+)
LP/J MGP_LPJ_G0022622
 protein coding gene Chr16:29192049-29228320 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0022549
 protein coding gene Chr16:30759422-30801198 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0023148
 protein coding gene Chr16:29037999-29076078 (+)
PWK/PhJ MGP_PWKPhJ_G0021719
 protein coding gene Chr16:28210365-28247615 (+)
SPRET/EiJ MGP_SPRETEiJ_G0021550
 protein coding gene Chr16:28818363-28861484 (+)
WSB/EiJ MGP_WSBEiJ_G0022024
 protein coding gene Chr16:28976964-29018848 (+)



Homology
more
  • Human Ortholog
    BDH1, 3-hydroxybutyrate dehydrogenase 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BDH1, 3-hydroxybutyrate dehydrogenase 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    BDH, SDR9C1
  • Links
    NCBI Gene ID: 622
    neXtProt AC: NX_Q02338
    UniProt: Q02338

  • Chr Location
    3q29; chr3:197509783-197573323 (-)  GRCh38.p7
  • HomoloGene
    Vertebrate Homology Class 20860
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BDH1
  • Gene Tree
    Bdh1
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    8 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    14
  • GO References
    7
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    321
  • Tissues
    123
  • cDNA Data
    106
  • Literature Summary
    5
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 71911 NCBI Gene Model | MGI Sequence Detail 36605 C57BL/6J ±  kb
transcript NM_001122683 RefSeq | MGI Sequence Detail 3133 C57BL/6  
polypeptide Q80XN0 UniProt | EBI | MGI Sequence Detail 343 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • EC
    1.1.1.30
  • InterPro Domains
    IPR036291 NAD(P)-binding domain superfamily
    IPR020904 Short-chain dehydrogenase/reductase, conserved site
    IPR002347 Short-chain dehydrogenase/reductase SDR
Molecular
Reagents
less
  • All nucleic 107
    cDNA 106
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:2146421
References
more
  • Summaries
    All 43
    Developmental Gene Expression 5
    Gene Ontology 7
    Phenotypes 8
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:249661 Schatton D, et al., CLUH regulates mitochondrial metabolism by controlling translation and decay of target mRNAs. J Cell Biol. 2017 Mar 06;216(3):675-693
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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Send questions and comments to User Support. 		last database update
01/15/2019
MGI 6.13 		The Jackson Laboratory