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Ces2f Gene Detail
Summary
  • Symbol
    Ces2f
  • Name
    carboxylesterase 2F
  • Synonyms
    2310038E17Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919153
    NCBI Gene: 71903
  • Gene Overview
    MyGene.info: CES2
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:104947356-104960047 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 8, 53.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    17 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919153
protein coding gene Chr8:104947355-104961130 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034022
protein coding gene Chr8:107137421-107149935 (+)
A/J MGP_AJ_G0034003
protein coding gene Chr8:102924736-102933269 (+)
AKR/J MGP_AKRJ_G0033929
protein coding gene Chr8:105864942-105875404 (+)
BALB/cJ MGP_BALBcJ_G0033996
protein coding gene Chr8:103086794-103095310 (+)
C3H/HeJ MGP_C3HHeJ_G0033708
protein coding gene Chr8:106621233-106630023 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034516
protein coding gene Chr8:111102821-111111362 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031458
protein coding gene Chr8:96073031-96084274 (+)
CAST/EiJ MGP_CASTEiJ_G0033035
protein coding gene Chr8:106104325-106112870 (+)
CBA/J MGP_CBAJ_G0033682
protein coding gene Chr8:114695538-114704054 (+)
DBA/2J MGP_DBA2J_G0033836
protein coding gene Chr8:102227773-102236138 (+)
FVB/NJ MGP_FVBNJ_G0033783
protein coding gene Chr8:101157225-101165760 (+)
LP/J MGP_LPJ_G0033927
protein coding gene Chr8:107359810-107370903 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033825
protein coding gene Chr8:117927534-117936057 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034534
protein coding gene Chr8:105814540-105823899 (+)
PWK/PhJ MGP_PWKPhJ_G0032736
protein coding gene Chr8:101631827-101640906 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032576
protein coding gene Chr8:104543717-104552197 (+)
WSB/EiJ MGP_WSBEiJ_G0033150
protein coding gene Chr8:106505090-106514793 (+)



Homology
more
  • Human Ortholog
    CES2, carboxylesterase 2
  • Vertebrate Orthologs
    2
  • Human Ortholog
    CES2, carboxylesterase 2
    Orthology source: HGNC
  • Synonyms
    CE-2, CES2A1, iCE, PCE-2
  • Links
    NCBI Gene ID: 8824
    neXtProt AC: NX_O00748
    UniProt: O00748

  • Chr Location
    16q22.1; chr16:66934444-66945096 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotypes from 2 alleles in 2 genetic backgrounds
    6 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for an ENU-induced mutation exhibit epidermal and follicular hyperkeratosis.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000062826 Ensembl Gene Model | MGI Sequence Detail 12692 C57BL/6J ±  kb
transcript ENSMUST00000076384 Ensembl | MGI Sequence Detail 1823 Not Applicable  
polypeptide ENSMUSP00000075722 Ensembl | MGI Sequence Detail 561 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 10
    cDNA 10

    Microarray probesets 3
References
more
  • Summaries
    All 23
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:234901 Potter PK, et al., Novel gene function revealed by mouse mutagenesis screens for models of age-related disease. Nat Commun. 2016;7:12444

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory