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Noxo1
Gene Detail
 Symbol
Name
ID
Noxo1
NADPH oxidase organizer 1
MGI:1919143
Synonyms 2310034C04Rik
Feature Type protein coding gene
Genetic Map
Chromosome 17
12.49 cM, cytoband A3.3
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr17:24696234-24700529 bp, + strand
From VEGA annotation of GRCm38

  4296 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:12418  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog

Gene Tree: Noxo1

Human
homologs
Human Homolog NOXO1, NADPH oxidase organizer 1
NCBI Gene ID 124056
neXtProt AC  NX_Q8NFA2
Human Synonyms  P41NOX, P41NOXA, P41NOXB, P41NOXC, SH3PXD5, SNX28
Human Chr (Location)  16p13.3; chr16:1978917-1981703 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Gene trapped(1) Spontaneous(1) Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
 
Mutations at this locus affect the inner ear and result in vestibular related movement anomalies.
 
Interactions
Noxo1 interacts with 25 markers (Mir92-1, Mir101a, Mir101b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (11 annotations)
Process extracellular matrix disassembly, positive regulation of catalytic activity, ...
Component membrane, NADPH oxidase complex, ...
Function enzyme binding, identical protein binding, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (12)    Tissues (3)    Images (12)
Theiler Stages: 23
Assay TypeResults
RNA in situ 12
cDNA source data(39)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(39) cDNA(39)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000021039 (Evidence)
Ensembl Gene ModelENSMUSG00000019320 (Evidence)
Entrez Gene71893 (Evidence)
UniGene390971
DFCITC1582312, TC1592331
Consensus CDS ProjectCCDS50018.1
International Mouse Knockout Project StatusNoxo1
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021039 VEGA Gene Model | MGI Sequence Detail 4296 C57BL/6J ±  kb
transcript OTTMUST00000049755 VEGA | MGI Sequence Detail 2238 Not Applicable 
polypeptide OTTMUSP00000023108 VEGA | MGI Sequence Detail 349 Not Applicable 

For the selected sequences
All sequences(56) RefSeq(16) UniProt(3)
Polymorphisms SNPs within 2kb(61 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001683 Phox homologous domain
InterPro IPR001452 Src homology-3 domain
Protein Ontology PR:000011343 NADPH oxidase organizer 1
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:196582 Romand R, et al., Retinoic acid deficiency impairs the vestibular function. J Neurosci. 2013 Mar 27;33(13):5856-66
All references(33)
Other
accession IDs
MGI:2675599

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory