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Coq2 Gene Detail
Summary
  • Symbol
    Coq2
  • Name
    coenzyme Q2 4-hydroxybenzoate polyprenyltransferase
  • Synonyms
    2310002F18Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919133
    NCBI Gene: 71883
  • Gene Overview
    MyGene.info: COQ2
  • Alliance
  • Transcription Start Sites
    1 TSS
Location &
Maps
more
  • Sequence Map
    Chr5:100654723-100674289 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 5, 48.50 cM, cytoband E3
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    257 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919133
protein coding gene Chr5:100654723-100675140 (-)
129S1/SvImJ MGP_129S1SvImJ_G0029789
protein coding gene Chr5:102160476-102180005 (-)
A/J MGP_AJ_G0029755
protein coding gene Chr5:98351937-98371458 (-)
AKR/J MGP_AKRJ_G0029701
protein coding gene Chr5:101589949-101612431 (-)
BALB/cJ MGP_BALBcJ_G0029765
protein coding gene Chr5:99383738-99403267 (-)
C3H/HeJ MGP_C3HHeJ_G0029488
protein coding gene Chr5:101943884-101963392 (-)
C57BL/6NJ MGP_C57BL6NJ_G0030220
protein coding gene Chr5:106407780-106427307 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0027455
protein coding gene Chr5:93597121-93616547 (-)
CAST/EiJ MGP_CASTEiJ_G0028899
protein coding gene Chr5:100601350-100621713 (-)
CBA/J MGP_CBAJ_G0029458
protein coding gene Chr5:110099406-110118919 (-)
DBA/2J MGP_DBA2J_G0029602
protein coding gene Chr5:98545717-98565224 (-)
FVB/NJ MGP_FVBNJ_G0029561
protein coding gene Chr5:97346132-97365644 (-)
LP/J MGP_LPJ_G0029690
protein coding gene Chr5:102774261-102793784 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0029590
protein coding gene Chr5:115166510-115186039 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0030253
protein coding gene Chr5:101074333-101093851 (-)
PWK/PhJ MGP_PWKPhJ_G0028617
protein coding gene Chr5:96979770-96999707 (-)
SPRET/EiJ MGP_SPRETEiJ_G0028452
protein coding gene Chr5:98747056-98767629 (-)
WSB/EiJ MGP_WSBEiJ_G0028977
protein coding gene Chr5:101405823-101429606 (-)



Homology
more
  • Human Ortholog
    COQ2, coenzyme Q2, polyprenyltransferase
  • Vertebrate Orthologs
    10
  • Human Ortholog
    COQ2, coenzyme Q2, polyprenyltransferase
    Orthology source: HomoloGene, HGNC
  • Synonyms
    CL640, COQ10D1, MSA1, PHB:PPT
  • Links
    NCBI Gene ID: 27235
    UniProt: Q96H96

  • Chr Location
    4q21.22-q21.23; chr4:83138568-83285129 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 69192
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: COQ2
  • Gene Tree
Human Diseases
more
  • Diseases
    1 with human COQ2 associations

Human Disease Mouse Models
      
IDs
Click on a disease name to see all genes associated with that disease.

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 1 allele in 1 genetic background
    13 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71883 NCBI Gene Model | MGI Sequence Detail 19567 C57BL/6J ±  kb
    transcript NM_027978 RefSeq | MGI Sequence Detail 1712 C57BL/6  
    polypeptide Q66JT7 UniProt | EBI | MGI Sequence Detail 374 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 60
      cDNA 60

      Microarray probesets 3
    References
    more
    • Summaries
      All 42
      Developmental Gene Expression 3
      Gene Ontology 8
      Phenotypes 13
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
    Citing These Resources
    Funding Information
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    last database update
    11/06/2018
    MGI 6.13
    The Jackson Laboratory