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Serinc2 Gene Detail
Summary
  • Symbol
    Serinc2
  • Name
    serine incorporator 2
  • Synonyms
    2310004K20Rik, FKSG84, TDE2, Tde2l
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919132
    NCBI Gene: 230779
  • Alliance
  • Transcription Start Sites
    5 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:130253495-130279200 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 63.43 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    268 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919132
protein coding gene Chr4:130253495-130279205 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028847
protein coding gene Chr4:132255955-132285400 (-)
A/J MGP_AJ_G0028806
protein coding gene Chr4:126945863-126971410 (-)
AKR/J MGP_AKRJ_G0028759
protein coding gene Chr4:130503438-130529012 (-)
BALB/cJ MGP_BALBcJ_G0028829
protein coding gene Chr4:127558471-127584469 (-)
C3H/HeJ MGP_C3HHeJ_G0028543
protein coding gene Chr4:130561037-130589003 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029271
protein coding gene Chr4:137200990-137226706 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026543
protein coding gene Chr4:120061121-120087632 (-)
CAST/EiJ MGP_CASTEiJ_G0027975
protein coding gene Chr4:128771141-128798423 (-)
CBA/J MGP_CBAJ_G0028509
protein coding gene Chr4:140693557-140729163 (-)
DBA/2J MGP_DBA2J_G0028658
protein coding gene Chr4:127380343-127406255 (-)
FVB/NJ MGP_FVBNJ_G0028625
protein coding gene Chr4:126166509-126192244 (-)
LP/J MGP_LPJ_G0028759
protein coding gene Chr4:132578795-132606058 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028651
protein coding gene Chr4:145397353-145425701 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029309
protein coding gene Chr4:130873906-130900846 (-)
PWK/PhJ MGP_PWKPhJ_G0027697
protein coding gene Chr4:124004942-124032131 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027523
protein coding gene Chr4:126738251-126764388 (-)
WSB/EiJ MGP_WSBEiJ_G0028056
protein coding gene Chr4:131025944-131052570 (-)



Homology
more
  • Human Ortholog
    SERINC2, serine incorporator 2
  • Vertebrate Orthologs
    11
  • Human Ortholog
    SERINC2, serine incorporator 2
    Orthology source: HomoloGene, HGNC
  • Synonyms
    FKSG84, PRO0899, TDE2, TDE2L
  • Links
    NCBI Gene ID: 347735
    neXtProt AC: NX_Q96SA4
    UniProt: Q96SA4

  • Chr Location
    1p35.2; chr1:31409565-31434680 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 230779 NCBI Gene Model | MGI Sequence Detail 25706 C57BL/6J ±  kb
transcript NM_001356465 RefSeq | MGI Sequence Detail 5303 C57BL/6  
polypeptide Q8K0E7 UniProt | EBI | MGI Sequence Detail 450 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    6 Sequences
  • InterPro Domains
    IPR029554 Serine incorporator 2
    IPR005016 Serine incorporator/TMS membrane protein
Molecular
Reagents
less
  • All nucleic 106
    cDNA 106

    Microarray probesets 3
Other
Accession IDs
less
MGI:2140556
References
more
  • Summaries
    All 28
    Gene Ontology 3
    Phenotypes 6
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:99680 The FANTOM Consortium and RIKEN Genome Exploration Research Group and Genome Science Group (Genome Network Project Core Group), The Transcriptional Landscape of the Mammalian Genome. Science. 2005;309(5740):1559-1563

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
03/13/2019
MGI 6.13
The Jackson Laboratory