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Serpinb12
Gene Detail
 Symbol
Name
ID
Serpinb12
serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
MGI:1919119
Synonyms 2300003F07Rik, 4833409F13Rik
Feature Type protein coding gene
Genetic Map
Chromosome 1
50.34 cM, cytoband D
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr1:106934449-106957080 bp, + strand
From VEGA annotation of GRCm38

  22632 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23631  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken

Protein SuperFamily: serpin
Gene Tree: Serpinb12

Human
homologs
Human Homolog SERPINB12, serpin peptidase inhibitor, clade B (ovalbumin), member 12
NCBI Gene ID 89777
neXtProt AC  NX_Q96P63
Human Synonyms  YUKOPIN
Human Chr (Location)  18q21.33; chr18:63556160-63567103 (+)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(1) : Targeted(1)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Serpinb12 interacts with 77 markers (Mir1a-1, Mir1a-2, Mir15a, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (12 annotations)
Process hematopoietic progenitor cell differentiation, negative regulation of endopeptidase activity, ...
Component cytoplasm, extracellular space, ...
Function peptidase inhibitor activity, serine-type endopeptidase inhibitor activity
External Resources: FuncBase
Expression
cDNA source data(9)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(13) Genomic(4) cDNA(9)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021002 (Evidence)
Ensembl Gene ModelENSMUSG00000059956 (Evidence)
Entrez Gene71869 (Evidence)
UniGene321740
DFCITC1582430, TC1594325, TC1674252
DoTSDT.101172737, DT.40185725, DT.55139892, DT.94153362
NIA Mouse Gene IndexU000685
Consensus CDS ProjectCCDS15212.1
International Mouse Knockout Project StatusSerpinb12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021002 VEGA Gene Model | MGI Sequence Detail 22632 C57BL/6J ±  kb
transcript OTTMUST00000049652 VEGA | MGI Sequence Detail 1689 Not Applicable 
polypeptide OTTMUSP00000023039 VEGA | MGI Sequence Detail 423 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(4) UniProt(2)
Polymorphisms SNPs within 2kb(226 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR023795 Protease inhibitor I4, serpin, conserved site
InterPro IPR023796 Serpin domain
InterPro IPR000215 Serpin family
Protein Ontology PR:000014692 serpin B12
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17
All references(32)
Other
accession IDs
MGI:1921151

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
09/23/2014
MGI 5.19
The Jackson Laboratory