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Serpinb12 Gene Detail
Summary
  • Symbol
    Serpinb12
  • Name
    serine (or cysteine) peptidase inhibitor, clade B (ovalbumin), member 12
  • Synonyms
    2300003F07Rik, 4833409F13Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919119
    NCBI Gene: 71869
Location & Maps
more
  • Sequence Map
    Chr1:106934449-106957080 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22632 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    SERPINB12, serpin peptidase inhibitor, clade B (ovalbumin), member 12
  • Vertebrate Orthologs
    8
  • Human Ortholog
    SERPINB12, serpin peptidase inhibitor, clade B (ovalbumin), member 12
    Orthology source: HomoloGene
  • Synonyms
    YUKOPIN
  • Links
    NCBI Gene ID: 89777
    neXtProt AC: NX_Q96P63

  • Chr Location
    18q21.33; chr18:63519090-63569329 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
  • All Mutations and Alleles
    5
  • Chemically induced (other)
    2
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    3 involving Serpinb12
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021002 VEGA Gene Model | MGI Sequence Detail 22632 C57BL/6J ±  kb
transcript OTTMUST00000049653 VEGA | MGI Sequence Detail 1623 Not Applicable  
polypeptide OTTMUSP00000023040 VEGA | MGI Sequence Detail 423 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    226 from dbSNP Build 137
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 13
    Genomic 4
    cDNA 9

    Microarray probesets 4
Other
Accession IDs
less
MGI:1921151
References
more
  • Summaries
    All 27
    Gene Ontology 5
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:202604 Nagamachi A, et al., Haploinsufficiency of SAMD9L, an endosome fusion facilitator, causes myeloid malignancies in mice mimicking human diseases with monosomy 7. Cancer Cell. 2013 Sep 9;24(3):305-17

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory