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Dpep3
Gene Detail
Symbol

Name
ID
Dpep3
dipeptidase 3
MGI:1919104
Synonyms
1700018F16Rik, MBD-3
Feature Type
protein coding gene
Genetic Map
Chromosome 8
53.07 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr8:105973520-105979419 bp, - strand
From NCBI annotation of GRCm38

  5900 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:23357  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

HCOP human homology predictions: DPEP3
Protein SuperFamily: membrane dipeptidase
Gene Tree: Dpep3

Human
homologs
DPEP3, dipeptidase 3
Orthology source: HGNC, HomoloGene

IDs:
NCBI Gene ID: 64180
neXtProt AC: NX_Q9H4B8

Human Synonyms: MBD3

Human Chr (Location): 16q22.1; chr16:67975663-67980549 (-)  GRCh38.p2

Mutations,
alleles, and
phenotypes
All mutations/alleles(15) : Gene trapped(10) Targeted(5)
Incidental mutations (data from Mutagenetix , APF , CvDC )
Interactions
Dpep3 interacts with 10 markers (Mir18b, Mir325, Mir495, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (13 annotations)
Process meiotic cell cycle, proteolysis
Component anchored component of membrane, membrane
Function dipeptidase activity, dipeptidyl-peptidase activity, ...
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (10)    Tissues (9)    Tissue x Stage Matrix (view)
Assay TypeResults
RT-PCR 10
cDNA source data(19)
Other mouse links: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(20) cDNA(19) Primer pair(1)
Microarray probesets(4)
Other database
links
Ensembl Gene Model ENSMUSG00000031898 (Evidence)
Entrez Gene 71854 (Evidence)
UniGene 173395
DFCI TC1583869
DoTS DT.40168176, DT.94223065
EC 3.4.13.19
Consensus CDS Project CCDS22624.1
International Mouse Phenotyping Consortium Status Dpep3
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic 71854 NCBI Gene Model | MGI Sequence Detail 5900 C57BL/6J ±  kb
transcript NM_027960 RefSeq | MGI Sequence Detail 1681 C57BL/6 
polypeptide Q9DA79 UniProt | EBI | MGI Sequence Detail 493 Not Applicable 

For the selected sequences
All sequences(15) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(20 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR008257 Peptidase M19, renal dipeptidase
InterPro IPR000180 Peptidase M19, renal dipeptidase, active site
Protein Ontology PR:000006648 dipeptidase 3
Graphical View of Protein Domain Structure
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:193640 Lo JC, et al., RAB-like 2 has an essential role in male fertility, sperm intra-flagellar transport, and tail assembly. PLoS Genet. 2012;8(10):e1002969
All references(35)
Other
accession IDs
MGI:2142580

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory