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Dcaf7 Gene Detail
Summary
  • Symbol
    Dcaf7
  • Name
    DDB1 and CUL4 associated factor 7
  • Synonyms
    1700012F10Rik, 2610037L01Rik, Wdr68
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919083
    NCBI Gene: 71833
  • Gene Overview
    MyGene.info: DCAF7
Location & Maps
more
  • Sequence Map
    Chr11:106036872-106059324 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      22453 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 11, 68.89 cM, cytoband E1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    DCAF7, DDB1 and CUL4 associated factor 7
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DCAF7, DDB1 and CUL4 associated factor 7
    Orthology source: HGNC, HomoloGene
  • Synonyms
    AN11, HAN11, SWAN-1, WDR68
  • Links
    NCBI Gene ID: 10238
    neXtProt AC: NX_P61962

  • Chr Location
    17q23.3; chr17:63550435-63594279 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 55930
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DCAF7
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000003052 VEGA Gene Model | MGI Sequence Detail 22453 C57BL/6J ±  kb
transcript OTTMUST00000006266 VEGA | MGI Sequence Detail 5750 Not Applicable  
polypeptide OTTMUSP00000002954 VEGA | MGI Sequence Detail 342 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    106 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000029377 DDB1- and CUL4-associated factor 7
  • InterPro Domains
    IPR001680 WD40 repeat
    IPR019775 WD40 repeat, conserved site
    IPR017986 WD40-repeat-containing domain
    IPR015943 WD40/YVTN repeat-like-containing domain
Molecular
Reagents
less
  • All nucleic 15
    cDNA 15

    Microarray probesets 7
Other
Accession IDs
less
MGI:1922876, MGI:2144685
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 2
    Phenotypes 6
  • Earliest
    J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory