About   Help   FAQ
Tmem50a Gene Detail
Summary
  • Symbol
    Tmem50a
  • Name
    transmembrane protein 50A
  • Synonyms
    3200001F09Rik, CAM, Smp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919067
    NCBI Gene: 71817
  • Gene Overview
    MyGene.info: TMEM50A
Location & Maps
more
  • Sequence Map
    Chr4:134897849-134915024 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17176 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 67.14 cM, cytoband D3
  • Detailed Genetic Map ± 1 cM
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
    Orthology source: HGNC, HomoloGene
  • Synonyms
    IFNRC, SMP1
  • Links
    NCBI Gene ID: 23585
    neXtProt AC: NX_O95807

  • Chr Location
    1p36.11; chr1:25338298-25362361 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
  • All Mutations and Alleles
    29
  • Chemically induced (other)
    2
  • Gene trapped
    23
  • Targeted
    4
  • Genomic Mutations
    3 involving Tmem50a
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000011093 VEGA Gene Model | MGI Sequence Detail 17176 C57BL/6J ±  kb
transcript OTTMUST00000025964 VEGA | MGI Sequence Detail 1204 Not Applicable  
polypeptide OTTMUSP00000011892 VEGA | MGI Sequence Detail 157 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    194 from dbSNP Build 142
Protein
Information
less
  • UniProt
    2 Sequences
  • Protein Ontology
    PR:000029810 transmembrane protein 50A
  • InterPro Domains
    IPR007919 Uncharacterised protein family UPF0220
Molecular
Reagents
less
  • All nucleic 137
    Genomic 1
    cDNA 136

    Microarray probesets 2
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 9
  • Earliest
    J:8214 Schuh R, et al., Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence. Proc Natl Acad Sci U S A. 1986 Mar;83(5):1364-8
  • Latest
    J:161922 Tang T, et al., A mouse knockout library for secreted and transmembrane proteins. Nat Biotechnol. 2010 Jul;28(7):749-55

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
05/24/2016
MGI 6.04
The Jackson Laboratory