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Tmem50a Gene Detail
Summary
  • Symbol
    Tmem50a
  • Name
    transmembrane protein 50A
  • Synonyms
    3200001F09Rik, CAM, Smp1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919067
    NCBI Gene: 71817
  • Gene Overview
    MyGene.info: TMEM50A
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr4:134897849-134915024 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 67.14 cM, cytoband D3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    194 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919067
protein coding gene Chr4:134897849-134915030 (-)
129S1/SvImJ MGP_129S1SvImJ_G0028936
protein coding gene Chr4:137284906-137304643 (-)
A/J MGP_AJ_G0028895
protein coding gene Chr4:131505557-131523886 (-)
AKR/J MGP_AKRJ_G0028847
protein coding gene Chr4:135283669-135311493 (-)
BALB/cJ MGP_BALBcJ_G0028919
protein coding gene Chr4:132158903-132176098 (-)
C3H/HeJ MGP_C3HHeJ_G0028633
protein coding gene Chr4:135529319-135550246 (-)
C57BL/6NJ MGP_C57BL6NJ_G0029360
protein coding gene Chr4:142229820-142254660 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0026631
protein coding gene Chr4:124558927-124574796 (-)
CAST/EiJ MGP_CASTEiJ_G0028065
protein coding gene Chr4:133658208-133679964 (-)
CBA/J MGP_CBAJ_G0028598
protein coding gene Chr4:146004385-146031194 (-)
DBA/2J MGP_DBA2J_G0028747
protein coding gene Chr4:131927023-131943909 (-)
FVB/NJ MGP_FVBNJ_G0028714
protein coding gene Chr4:130837932-130855961 (-)
LP/J MGP_LPJ_G0028846
protein coding gene Chr4:137395295-137413884 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0028740
protein coding gene Chr4:150442212-150460452 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0029398
protein coding gene Chr4:135728090-135746013 (-)
PWK/PhJ MGP_PWKPhJ_G0027785
protein coding gene Chr4:128675493-128696643 (-)
SPRET/EiJ MGP_SPRETEiJ_G0027611
protein coding gene Chr4:131556074-131574859 (-)
WSB/EiJ MGP_WSBEiJ_G0028143
protein coding gene Chr4:135900746-135919897 (-)



Homology
more
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
  • Vertebrate Orthologs
    10
  • Human Ortholog
    TMEM50A, transmembrane protein 50A
    Orthology source: HomoloGene, HGNC
  • Synonyms
    IFNRC, SMP1
  • Links
    NCBI Gene ID: 23585
    neXtProt AC: NX_O95807
    UniProt: O95807

  • Chr Location
    1p36.11; chr1:25338298-25362361 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    9 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000028822 Ensembl Gene Model | MGI Sequence Detail 17176 C57BL/6J ±  kb
transcript ENSMUST00000105863 Ensembl | MGI Sequence Detail 719 Not Applicable  
polypeptide ENSMUSP00000101489 Ensembl | MGI Sequence Detail 157 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 138
    Genomic 1
    cDNA 137

    Microarray probesets 2
References
more
  • Summaries
    All 35
    Developmental Gene Expression 2
    Gene Ontology 6
    Phenotypes 9
  • Earliest
    J:8214 Schuh R, et al., Molecular cloning of the mouse cell adhesion molecule uvomorulin: cDNA contains a B1-related sequence. Proc Natl Acad Sci U S A. 1986 Mar;83(5):1364-8
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory