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Ints12
Gene Detail
 Symbol
Name
ID
Ints12
integrator complex subunit 12
MGI:1919043
Synonyms 1110020M19Rik, 2810027J24Rik, 4930529N21Rik, A230056J18Rik, Phf22
Feature Type protein coding gene
Genetic Map
Chromosome 3
61.56 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr3:133091840-133110988 bp, + strand
From VEGA annotation of GRCm38

  19149 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32474  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Ints12

Human
homologs
Human Homolog INTS12, integrator complex subunit 12
NCBI Gene ID 57117
neXtProt AC  NX_Q96CB8
Human Synonyms  INT12, PHF22
Human Chr (Location)  4q24; chr4:105682627-105708724 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(14) : Gene trapped(12) Targeted(2)
Incidental mutations (data from Mutagenetix , APF )
Interactions
Ints12 interacts with 239 markers (Mir10b, Mir19a, Mir19b-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process snRNA processing
Component integrator complex, nucleus
Function metal ion binding, zinc ion binding
External Resources: FuncBase
Expression
Literature Summary: (3 records)
Data Summary: Results (53)    Tissues (53)    Images (5)
Theiler Stages: 2, 3, 4, 5, 16, 17, 21, 23, 27, 28
Assay TypeResults
RNA in situ 45
RT-PCR 8
cDNA source data(53)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(54) cDNA(53) Primer pair(1)
Microarray probesets(5)
Other database
links
VEGA Gene ModelOTTMUSG00000017460 (Evidence)
Ensembl Gene ModelENSMUSG00000028016 (Evidence)
Entrez Gene71793 (Evidence)
UniGene246726
DFCITC1578854, TC1598086, TC1598912
DoTSDT.489060, DT.91391554
NIA Mouse Gene IndexU003870
PDB1WEV
Consensus CDS ProjectCCDS17848.1
International Mouse Knockout Project StatusInts12
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000017460 VEGA Gene Model | MGI Sequence Detail 19149 C57BL/6J ±  kb
transcript OTTMUST00000042398 VEGA | MGI Sequence Detail 3101 Not Applicable 
polypeptide OTTMUSP00000019052 VEGA | MGI Sequence Detail 461 Not Applicable 

For the selected sequences
All sequences(33) RefSeq(2) UniProt(1)
Polymorphisms SNPs within 2kb(125 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR011011 Zinc finger, FYVE/PHD-type
InterPro IPR019787 Zinc finger, PHD-finger
InterPro IPR001965 Zinc finger, PHD-type
InterPro IPR019786 Zinc finger, PHD-type, conserved site
InterPro IPR013083 Zinc finger, RING/FYVE/PHD-type
Protein Ontology PR:000009068 integrator complex subunit 12
References (Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(40)
Other
accession IDs
MGI:1919937, MGI:1922431, MGI:2139786, MGI:2444032

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory