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Trnau1ap Gene Detail
Summary
  • Symbol
    Trnau1ap
  • Name
    tRNA selenocysteine 1 associated protein 1
  • Synonyms
    1110007F05Rik, SECp43, Trspap1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919037
    NCBI Gene: 71787
Location & Maps
more
  • Sequence Map
    Chr4:132311763-132329538 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17776 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 65.16 cM, cytoband D3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    TRNAU1AP, tRNA selenocysteine 1 associated protein 1
  • Vertebrate Orthologs
    8
  • Human Ortholog
    TRNAU1AP, tRNA selenocysteine 1 associated protein 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    PRO1902, SECP43, TRSPAP1
  • Links
    NCBI Gene ID: 54952
    neXtProt AC: NX_Q9NX07
    UniProt: Q9NX07

  • Chr Location
    1p35.3; chr1:28553017-28578545 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    5 phenotypes from 3 alleles in 3 genetic backgrounds
    9 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Mice homozygous for an allele lacking exons 7 and 8 exhibit prenatal lethality. Mice homozygous for a conditional allele activated in neurons exhibit impaired performance on a rotarod.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000009574 VEGA Gene Model | MGI Sequence Detail 17776 C57BL/6J ±  kb
transcript OTTMUST00000021958 VEGA | MGI Sequence Detail 1130 Not Applicable  
polypeptide OTTMUSP00000010013 VEGA | MGI Sequence Detail 287 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    197 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 42
    cDNA 41
    Primer pair 1

    Microarray probesets 4
Other
Accession IDs
less
MGI:3034225
References
more
  • Summaries
    All 37
    Developmental Gene Expression 1
    Gene Ontology 5
    Phenotypes 9
  • Earliest
    J:23094 Davisson MT, New chromosome aberrations. Mouse News Lett. 1988;80:166
  • Latest
    J:237714 Mahdi Y, et al., Expression of Selenoproteins Is Maintained in Mice Carrying Mutations in SECp43, the tRNA Selenocysteine 1 Associated Protein (Trnau1ap). PLoS One. 2015;10(6):e0127349

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
07/11/2017
MGI 6.10
The Jackson Laboratory