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Isyna1 Gene Detail
Summary
  • Symbol
    Isyna1
  • Name
    myo-inositol 1-phosphate synthase A1
  • Synonyms
    1300017C10Rik, inositol-3-phosphate synthase 1, myo-inositol 1-phosphate synthase A1
  • Feature Type
    protein coding gene
  • IDs
    MGI:1919030
    NCBI Gene: 71780
  • Alliance
    gene page
  • Transcription Start Sites
    9 TSS
Location &
Maps
more
  • Sequence Map
    Chr8:71047131-71049940 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 8, 34.15 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    117 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1919030
 protein coding gene Chr8:71047023-71049940 (+)
129S1/SvImJ MGP_129S1SvImJ_G0033713
 protein coding gene Chr8:70870114-70872922 (+)
A/J MGP_AJ_G0033696
 protein coding gene Chr8:67993695-67996502 (+)
AKR/J MGP_AKRJ_G0033621
 protein coding gene Chr8:69926311-69929101 (+)
BALB/cJ MGP_BALBcJ_G0033692
 protein coding gene Chr8:68226488-68229296 (+)
C3H/HeJ MGP_C3HHeJ_G0033402
 protein coding gene Chr8:70576332-70579140 (+)
C57BL/6NJ MGP_C57BL6NJ_G0034209
 protein coding gene Chr8:73550761-73553568 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0031153
 protein coding gene Chr8:62810365-62813134 (+)
CAST/EiJ MGP_CASTEiJ_G0032727
 protein coding gene Chr8:70066262-70069051 (+)
CBA/J MGP_CBAJ_G0033380
 protein coding gene Chr8:76186523-76189331 (+)
DBA/2J MGP_DBA2J_G0033534
 protein coding gene Chr8:67709122-67711930 (+)
FVB/NJ MGP_FVBNJ_G0033475
 protein coding gene Chr8:66835918-66838726 (+)
LP/J MGP_LPJ_G0033621
 protein coding gene Chr8:70898488-70901296 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0033518
 protein coding gene Chr8:78854357-78857164 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0034227
 protein coding gene Chr8:70112407-70115215 (+)
PWK/PhJ MGP_PWKPhJ_G0032435
 protein coding gene Chr8:67009950-67012757 (+)
SPRET/EiJ MGP_SPRETEiJ_G0032271
 protein coding gene Chr8:69079229-69082042 (+)
WSB/EiJ MGP_WSBEiJ_G0032842
 protein coding gene Chr8:70472656-70475446 (+)



Homology
more
  • Human Ortholog
    ISYNA1, inositol-3-phosphate synthase 1
  • Vertebrate Orthologs
    2
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    ISYNA1, inositol-3-phosphate synthase 1
  • Synonyms
    INO1, INOS, IPS, IPS 1, IPS-1
  • Links
    NCBI Gene ID: 51477
    UniProt: Q9NPH2

  • Chr Location
    19p13.11; chr19:18434388-18438167 (-)  GRCh38
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    14 phenotypes from 1 allele in 1 genetic background
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    720
  • Tissues
    7
  • cDNA Data
    185
  • Literature Summary
    4
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71780 NCBI Gene Model | MGI Sequence Detail 2810 C57BL/6J ±  kb
    transcript NM_023627 RefSeq | MGI Sequence Detail 1850 Not Specified  
    polypeptide Q9JHU9 UniProt | EBI | MGI Sequence Detail 557 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 188
      cDNA 185
      Primer pair 3

      Microarray probesets 4
    Other
    Accession IDs
    less
    MGI:2142685
    References
    more
    • Summaries
      All 37
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
    • Latest
      J:363264 Leung KY, et al., Association of embryonic inositol status with susceptibility to neural tube defects, metabolite profile, and maternal inositol intake. FASEB J. 2024 Jun 15;38(11):e23738
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    Send questions and comments to User Support.     		last database update
    03/25/2025
    MGI 6.24     		The Jackson Laboratory