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Gtf3c2
Gene Detail
 Symbol
Name
ID
Gtf3c2
general transcription factor IIIC, polypeptide 2, beta
MGI:1919002
Synonyms 1300004C11Rik, 2610510G03Rik, mKIAA0011, TFIIIC110, TFIIIC-BETA
Feature Type protein coding gene
Genetic Map
Chromosome 5
17.15 cM
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr5:31156005-31180144 bp, - strand
From VEGA annotation of GRCm38

  24140 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:37490  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Protein SuperFamily: human transcription factor IIIC2 beta chain
Gene Tree: Gtf3c2

Human
homologs
Human Homolog GTF3C2, general transcription factor IIIC, polypeptide 2, beta 110kDa
NCBI Gene ID 2976
neXtProt AC  NX_Q8WUA4
Human Synonyms  TFIIIC110, TFIIIC-BETA
Human Chr (Location)  2p23.3; chr2:27325849-27357034 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Radiation induced(2)
Genomic Mutations involving Gtf3c2 (2)
Incidental mutations (data from Mutagenetix , APF )
Alleles Annotated to Human Diseases(1)   
Interactions
Gtf3c2 interacts with 254 markers (Mir15a, Mir15b, Mir16-1, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (5 annotations)
Process transcription, DNA-templated, transcription from RNA polymerase III promoter
Component nucleus, transcription factor TFIIIC complex
Function DNA binding
External Resources: FuncBase
Expression
Literature Summary: (2 records)
Data Summary: Results (189)    Tissues (110)    Images (41)
Theiler Stages: 22, 23
Assay TypeResults
RNA in situ 189
cDNA source data(238)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(239) cDNA(238) Primer pair(1)
Microarray probesets(10)
Other database
links
VEGA Gene ModelOTTMUSG00000022465 (Evidence)
Ensembl Gene ModelENSMUSG00000029144 (Evidence)
Entrez Gene71752 (Evidence)
UniGene271923
DFCITC1573431, TC1580743, TC1596555, TC1597216, TC1621890, TC1646438
DoTSDT.101134089, DT.101313425, DT.101397767, DT.101397777, DT.101739652, DT.110647569, DT.40185895, DT.480776, DT.87069447, DT.97387627
Consensus CDS ProjectCCDS39053.1
International Mouse Knockout Project StatusGtf3c2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022465 VEGA Gene Model | MGI Sequence Detail 24140 C57BL/6J ±  kb
transcript OTTMUST00000053732 VEGA | MGI Sequence Detail 3933 Not Applicable 
polypeptide OTTMUSP00000025564 VEGA | MGI Sequence Detail 950 Not Applicable 

For the selected sequences
All sequences(104) RefSeq(14) UniProt(5)
Polymorphisms SNPs within 2kb(79 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR001680 WD40 repeat
InterPro IPR019775 WD40 repeat, conserved site
InterPro IPR017986 WD40-repeat-containing domain
InterPro IPR015943 WD40/YVTN repeat-like-containing domain
Protein Ontology PR:000008326 general transcription factor 3C polypeptide 2
References (Earliest) J:60984 Ko MS, et al., Large-scale cDNA analysis reveals phased gene expression patterns during preimplantation mouse development. Development. 2000 Apr;127(8):1737-49
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(30)
Other
accession IDs
MGI:1914747, MGI:2140819, MGI:2141080

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
09/09/2014
MGI 5.19
The Jackson Laboratory