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Rgl3 Gene Detail
Summary
  • Symbol
    Rgl3
  • Name
    ral guanine nucleotide dissociation stimulator-like 3
  • Synonyms
    1300003D20Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918996
    NCBI Gene: 71746
Location & Maps
more
  • Sequence Map
    Chr9:21971527-21989453 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      17927 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 7.96 cM, cytoband A4
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    RGL3, ral guanine nucleotide dissociation stimulator like 3
  • Vertebrate Orthologs
    7
  • Human Ortholog
    RGL3, ral guanine nucleotide dissociation stimulator like 3
    Orthology source: HGNC, HomoloGene
  • Links
    NCBI Gene ID: 57139
    neXtProt AC: NX_Q3MIN7

  • Chr Location
    19p13.2; chr19:11394056-11419342 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    2 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000040146 Ensembl Gene Model | MGI Sequence Detail 17927 C57BL/6J ±  kb
transcript ENSMUST00000045726 Ensembl | MGI Sequence Detail 2550 Not Applicable  
polypeptide ENSMUSP00000035726 Ensembl | MGI Sequence Detail 709 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    50 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000013938 ral guanine nucleotide dissociation stimulator-like 3
  • InterPro Domains
    IPR030750 Ral guanine nucleotide dissociation stimulator-like 3
    IPR000159 Ras-associating (RA) domain
    IPR019804 Ras guanine-nucleotide exchange factor, conserved site
    IPR023578 Ras guanine nucleotide exchange factor domain
    IPR001895 Ras guanine-nucleotide exchange factors catalytic domain
    IPR000651 Ras-like guanine nucleotide exchange factor, N-terminal
    IPR029071 Ubiquitin-related domain
Molecular
Reagents
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  • All nucleic 30
    cDNA 28
    Other 2

    Microarray probesets 2
References
more
  • Summaries
    All 21
    Developmental Gene Expression 1
    Gene Ontology 3
    Phenotypes 2
  • Earliest
    J:64313 Shao H, et al., A novel RalGEF-like protein, RGL3, as a candidate effector for rit and Ras. J Biol Chem. 2000 Sep 1;275(35):26914-24
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/19/2016
MGI 6.04
The Jackson Laboratory