Pvrl4
Gene Detail

Symbol Name ID

Pvrl4 poliovirus receptor-related 4 MGI:1918990

Synonyms

1200017F15Rik, nectin 4, Prr4

Feature Type

protein coding gene

Genetic Map

Chromosome 1

79.37 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(2)

Sequence Map

Chr1:171370099-171388598 bp, + strand From VEGA annotation of GRCm38   18500 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:32744  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 zebrafish

Protein SuperFamily: poliovirus receptor-related protein
Gene Tree: Pvrl4

Human homologs

Human Homolog		PVRL4, poliovirus receptor-related 4
NCBI Gene ID		81607
neXtProt AC		NX_Q96NY8
Human Synonyms		EDSS1, LNIR, nectin-4, PRR4
Human Chr (Location)		1q22-q23.2; chr1:161040781-161059385 (-)  GRCh37.p10
Disease Associations		(1) Diseases Associated with Human PVRL4

Alleles and phenotypes

All alleles(2) : Gene trapped(2)

Gene Ontology (GO) classifications

All GO classifications: (8 annotations)

Process	cell adhesion, cell-cell adhesion
Component	adherens junction, cell junction, ...
Function	molecular_function

External Resources: FuncBase

Expression

Literature Summary: (5 records)
Data Summary: Results (111)    Tissues (31)    Images (22)
Theiler Stages: 10, 18, 23, 25, 28

Assay Type	Results
RNA in situ	99
Northern blot	12

cDNA source data(24)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(24) cDNA(24)
Microarray probesets(4)

Other database links

VEGA Gene Model	OTTMUSG00000021602 (Evidence)
Ensembl Gene Model	ENSMUSG00000006411 (Evidence)
Entrez Gene	71740 (Evidence)
UniGene	263414
DFCI	TC1582105, TC1593372, TC1596147, TC1682603
DoTS	DT.40141569, DT.40158121, DT.55196800
NIA Mouse Gene Index	U001086
Consensus CDS Project	CCDS15493.1, CCDS48442.1
International Mouse Knockout Project Status	Pvrl4

Sequences

Length	Strain/Species
genomic	OTTMUSG00000021602	VEGA Gene Model | MGI Sequence Detail	18500	C57BL/6J
transcript	OTTMUST00000051296	VEGA | MGI Sequence Detail	3201	Not Applicable
polypeptide	OTTMUSP00000024103	VEGA | MGI Sequence Detail	572	Not Applicable

All sequences(37) RefSeq(4) UniProt(2)

Polymorphisms

SNPs(140 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR013162	CD80-like, immunoglobulin C2-set
InterPro	IPR013151	Immunoglobulin
InterPro	IPR007110	Immunoglobulin-like
InterPro	IPR013783	Immunoglobulin-like fold
InterPro	IPR003599	Immunoglobulin subtype
InterPro	IPR003598	Immunoglobulin subtype 2
InterPro	IPR013106	Immunoglobulin V-set
Protein Ontology	PR:000013503	poliovirus receptor-related protein 4

References

(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(32)