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Pvrl4
Gene Detail
Symbol

Name
ID
Pvrl4
poliovirus receptor-related 4
MGI:1918990
Synonyms
1200017F15Rik, nectin 4, Prr4
Feature Type
protein coding gene
Genetic Map
Chromosome 1
79.37 cM, cytoband H2
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr1:171370099-171388598 bp, + strand
From VEGA annotation of GRCm38

  18500 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:32744  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 2 zebrafish

Protein SuperFamily: poliovirus receptor-related protein
Gene Tree: Pvrl4

Human
homologs
Human Homolog PVRL4, poliovirus receptor-related 4
NCBI Gene ID 81607
neXtProt AC  NX_Q96NY8
Human Synonyms  EDSS1, LNIR, nectin-4, PRR4
Human Chr (Location)  1q22-q23.2; chr1:161070991-161089595 (-)  GRCh38
Disease Associations  (1) Diseases Associated with Human PVRL4
Mutations,
alleles, and
phenotypes
All mutations/alleles(2) : Gene trapped(2)
Incidental mutations (data from APF )
Interactions
Pvrl4 interacts with 209 markers (Mir1a-1, Mir1a-2, Mir1b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (9 annotations)
Process cell adhesion, single organismal cell-cell adhesion
Component adherens junction, cell junction, ...
Function molecular_function
External Resources: FuncBase
Expression
Literature Summary: (5 records)
Data Summary: Results (115)    Tissues (35)    Images (28)    Tissue x Stage Matrix (view)
Assay TypeResults
RNA in situ 103
Northern blot 12
cDNA source data(23)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(24) cDNA(24)
Microarray probesets(4)
Other database
links
VEGA Gene ModelOTTMUSG00000021602 (Evidence)
Ensembl Gene ModelENSMUSG00000006411 (Evidence)
Entrez Gene71740 (Evidence)
UniGene263414
DFCITC1582105, TC1593372, TC1682603, TC1596147
DoTSDT.55196800, DT.40158121, DT.40141569
NIA Mouse Gene IndexU001086
Consensus CDS ProjectCCDS15493.1, CCDS48442.1
International Mouse Knockout Project StatusPvrl4
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000021602 VEGA Gene Model | MGI Sequence Detail 18500 C57BL/6J ±  kb
transcript OTTMUST00000051296 VEGA | MGI Sequence Detail 3201 Not Applicable 
polypeptide OTTMUSP00000024103 VEGA | MGI Sequence Detail 572 Not Applicable 

For the selected sequences
All sequences(38) RefSeq(4) UniProt(3)
Polymorphisms
SNPs within 2kb(219 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR013162 CD80-like, immunoglobulin C2-set
InterPro IPR013151 Immunoglobulin
InterPro IPR007110 Immunoglobulin-like domain
InterPro IPR013783 Immunoglobulin-like fold
InterPro IPR003599 Immunoglobulin subtype
InterPro IPR003598 Immunoglobulin subtype 2
InterPro IPR013106 Immunoglobulin V-set
Protein Ontology PR:000013503 poliovirus receptor-related protein 4
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582
All references(33)

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/11/2014
MGI 5.20
The Jackson Laboratory