About   Help   FAQ
Stk11ip Gene Detail
Summary
  • Symbol
    Stk11ip
  • Name
    serine/threonine kinase 11 interacting protein
  • Synonyms
    1200014D22Rik, LIP1, LKB1IP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918978
    NCBI Gene: 71728
  • Alliance
    gene page
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75498173-75513979 bp, + strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
    Ensembl | UCSC | NCBI
  • Genetic Map
    Chromosome 1, 39.16 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    117 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918978
 protein coding gene Chr1:75498173-75513979 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016193
 protein coding gene Chr1:76107759-76125005 (+)
A/J MGP_AJ_G0016176
 protein coding gene Chr1:73450914-73467442 (+)
AKR/J MGP_AKRJ_G0016133
 protein coding gene Chr1:75492955-75508755 (+)
BALB/cJ MGP_BALBcJ_G0016131
 protein coding gene Chr1:73513819-73530332 (+)
C3H/HeJ MGP_C3HHeJ_G0015962
 protein coding gene Chr1:75815624-75831825 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016584
 protein coding gene Chr1:79062930-79078874 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014305
 protein coding gene Chr1:69007961-69023235 (+)
CAST/EiJ MGP_CASTEiJ_G0015546
 protein coding gene Chr1:75162938-75178636 (+)
CBA/J MGP_CBAJ_G0015935
 protein coding gene Chr1:81639044-81654642 (+)
DBA/2J MGP_DBA2J_G0016036
 protein coding gene Chr1:72767366-72783345 (+)
FVB/NJ MGP_FVBNJ_G0016039
 protein coding gene Chr1:71980980-71999376 (+)
LP/J MGP_LPJ_G0016108
 protein coding gene Chr1:77232911-77248899 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016059
 protein coding gene Chr1:84975539-84991301 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016631
 protein coding gene Chr1:75553245-75571245 (+)
PWK/PhJ MGP_PWKPhJ_G0015333
 protein coding gene Chr1:72245497-72261571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015111
 protein coding gene Chr1:74909697-74925437 (+)
WSB/EiJ MGP_WSBEiJ_G0015608
 protein coding gene Chr1:75363998-75379847 (+)



Homology
more
  • Human Ortholog
    STK11IP, serine/threonine kinase 11 interacting protein
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    STK11IP, serine/threonine kinase 11 interacting protein
  • Synonyms
    LIP1, LKB1IP, STK11IP1
  • Links
    NCBI Gene ID: 114790
    neXtProt AC: NX_Q8N1F8
    UniProt: Q8N1F8

  • Chr Location
    2q35; chr2:219597857-219616451 (+)  GRCh38
Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    5 phenotypes from 1 allele in 1 genetic background
    27 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
    8
  • GO References
    3
Molecular Function

Biological Process

Cellular Component

Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
    706
  • cDNA Data
    36
  • Comparison Matrix
    Gene Expression + Phenotype
    • Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic 71728 NCBI Gene Model | MGI Sequence Detail 15807 C57BL/6J ±  kb
    transcript NM_027886 RefSeq | MGI Sequence Detail 4474 C57BL/6  
    polypeptide Q3TAA7 UniProt | EBI | MGI Sequence Detail 1072 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    • UniProt
      1 Sequence
    • Protein Ontology
      PR:000015741 serine/threonine-protein kinase 11-interacting protein
      (term hierarchy)
    • InterPro Domains
      IPR032675 Leucine-rich repeat domain superfamily
      IPR031782 LKB1 serine/threonine kinase interacting protein 1, N-terminal
    Molecular
    Reagents
    less
    • All nucleic 36
      cDNA 36

      Microarray probesets 2
    Other
    Accession IDs
    less
    MGI:2138637
    References
    more
    • Summaries
      All 50
      Diseases 1
      Gene Ontology 3
      Phenotypes 27
    • Earliest
      J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
    • Latest
      J:324110 Zi Z, et al., Quantitative phosphoproteomic analyses identify STK11IP as a lysosome-specific substrate of mTORC1 that regulates lysosomal acidification. Nat Commun. 2022 Apr 1;13(1):1760
    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
    Citing These Resources
    Funding Information
    Warranty Disclaimer, Privacy Notice, Licensing, & Copyright
    Send questions and comments to User Support.     		last database update
    04/16/2024
    MGI 6.23     		The Jackson Laboratory