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Stk11ip Gene Detail
Summary
  • Symbol
    Stk11ip
  • Name
    serine/threonine kinase 11 interacting protein
  • Synonyms
    1200014D22Rik, LIP1, LKB1IP
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918978
    NCBI Gene: 71728
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:75521529-75537335 bp, + strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, 39.16 cM, cytoband C3
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    117 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918978
protein coding gene Chr1:75521529-75537335 (+)
129S1/SvImJ MGP_129S1SvImJ_G0016193
protein coding gene Chr1:76107759-76125005 (+)
A/J MGP_AJ_G0016176
protein coding gene Chr1:73450914-73467442 (+)
AKR/J MGP_AKRJ_G0016133
protein coding gene Chr1:75492955-75508755 (+)
BALB/cJ MGP_BALBcJ_G0016131
protein coding gene Chr1:73513819-73530332 (+)
C3H/HeJ MGP_C3HHeJ_G0015962
protein coding gene Chr1:75815624-75831825 (+)
C57BL/6NJ MGP_C57BL6NJ_G0016584
protein coding gene Chr1:79062930-79078874 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0014305
protein coding gene Chr1:69007961-69023235 (+)
CAST/EiJ MGP_CASTEiJ_G0015546
protein coding gene Chr1:75162938-75178636 (+)
CBA/J MGP_CBAJ_G0015935
protein coding gene Chr1:81639044-81654642 (+)
DBA/2J MGP_DBA2J_G0016036
protein coding gene Chr1:72767366-72783345 (+)
FVB/NJ MGP_FVBNJ_G0016039
protein coding gene Chr1:71980980-71999376 (+)
LP/J MGP_LPJ_G0016108
protein coding gene Chr1:77232911-77248899 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0016059
protein coding gene Chr1:84975539-84991301 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0016631
protein coding gene Chr1:75553245-75571245 (+)
PWK/PhJ MGP_PWKPhJ_G0015333
protein coding gene Chr1:72245497-72261571 (+)
SPRET/EiJ MGP_SPRETEiJ_G0015111
protein coding gene Chr1:74909697-74925437 (+)
WSB/EiJ MGP_WSBEiJ_G0015608
protein coding gene Chr1:75363998-75379847 (+)



Homology
more
  • Human Ortholog
    STK11IP, serine/threonine kinase 11 interacting protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    STK11IP, serine/threonine kinase 11 interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    LIP1, LKB1IP, STK11IP1
  • Links
    NCBI Gene ID: 114790
    neXtProt AC: NX_Q8N1F8
    UniProt: Q8N1F8

  • Chr Location
    2q35; chr2:219597851-219616451 (+)  GRCh38.p7

Human Diseases
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  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    24 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    19
  • Chemically induced (other)
    1
  • Endonuclease-mediated
    1
  • Gene trapped
    11
  • Radiation induced
    2
  • Spontaneous
    1
  • Targeted
    3
  • Genomic Mutations
    4 involving Stk11ip
  • Incidental Mutations
  • Find Mice (IMSR)
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 71728 NCBI Gene Model | MGI Sequence Detail 15807 C57BL/6J ±  kb
transcript NM_027886 RefSeq | MGI Sequence Detail 4474 C57BL/6  
polypeptide Q3TAA7 UniProt | EBI | MGI Sequence Detail 1072 Not Applicable  
For the selected sequence
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000015741 serine/threonine-protein kinase 11-interacting protein
  • InterPro Domains
    IPR032675 Leucine-rich repeat domain superfamily
    IPR031782 LKB1 serine/threonine kinase interacting protein 1, N-terminal
Molecular
Reagents
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  • All nucleic 36
    cDNA 36

    Microarray probesets 2
Other
Accession IDs
less
MGI:2138637
References
more
  • Summaries
    All 46
    Diseases 1
    Gene Ontology 2
    Phenotypes 24
  • Earliest
    J:134667 Roderick TH, et al., Two radiation-induced chromosomal inversions in mice (Mus musculus). Proc Natl Acad Sci U S A. 1970 Oct;67(2):961-7
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
05/19/2020
MGI 6.15
The Jackson Laboratory