Osbpl3
Gene Detail

Symbol Name ID

Osbpl3 oxysterol binding protein-like 3 MGI:1918970

Synonyms

1200014M06Rik, 6720421I08Rik, ORP3, OSBP3

Feature Type

protein coding gene

Genetic Map

Chromosome 6

24.13 cM, cytoband B3
Detailed Genetic Map ± 1 cM


Mapping data(3)

Sequence Map

Chr6:50293330-50456201 bp, - strand From VEGA annotation of GRCm38   162872 bp   ±  kb flank VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer

Mouse Genome Browser

Vertebrate homology

HomoloGene:49422  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 zebrafish

Gene Tree: Osbpl3

Human homologs

Human Homolog		OSBPL3, oxysterol binding protein-like 3
NCBI Gene ID		26031
neXtProt AC		NX_Q9H4L5
Human Synonyms		ORP3, ORP-3, OSBP3
Human Chr (Location)		7p15; chr7:24836159-25019760 (-)  GRCh37.p10

Alleles and phenotypes

All alleles(28) : Targeted(2) Gene trapped(26)

Gene Ontology (GO) classifications

All GO classifications: (9 annotations)

Process	lipid transport, transport
Component	cytosol, nuclear membrane, ...
Function	cholesterol binding, lipid binding, ...

External Resources: FuncBase

Expression

Literature Summary: (3 records)
Data Summary: Results (182)    Tissues (37)    Images (33)
Theiler Stages: 10, 20, 23, 28

Assay Type	Results
RNA in situ	169
RT-PCR	13

cDNA source data(13)
External Resources: Allen Institute   GEO   ArrayExpress

Molecular reagents

All nucleic(16) cDNA(15) Primer pair(1)
Microarray probesets(5)

Other database links

VEGA Gene Model	OTTMUSG00000022235 (Evidence)
Ensembl Gene Model	ENSMUSG00000029822 (Evidence)
Entrez Gene	71720 (Evidence)
DFCI	TC1579593, TC1586511, TC1605411, TC1630908, TC1674313
DoTS	DT.101383568, DT.110476119, DT.40153137, DT.40156375, DT.40171394, DT.55251181
NIA Mouse Gene Index	U027286, U042735, U236768
Consensus CDS Project	CCDS39489.1, CCDS51771.1
International Mouse Knockout Project Status	Osbpl3

Sequences

Length	Strain/Species
genomic	OTTMUSG00000022235	VEGA Gene Model | MGI Sequence Detail	162872	C57BL/6J
transcript	OTTMUST00000052901	VEGA | MGI Sequence Detail	2661	Not Applicable
polypeptide	OTTMUSP00000025133	VEGA | MGI Sequence Detail	886	Not Applicable

All sequences(71) RefSeq(4) UniProt(6)

Polymorphisms

SNPs(751 from dbSNP Build 128)

Protein-related information

Resource	ID	Description
InterPro	IPR000648	Oxysterol-binding protein
InterPro	IPR018494	Oxysterol-binding protein, conserved site
InterPro	IPR001849	Pleckstrin homology domain
InterPro	IPR011993	Pleckstrin homology-like domain
Protein Ontology	PR:000012049	oxysterol-binding protein-related protein 3

References

(Earliest) J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
(Latest) J:193047 Revil T, et al., During embryogenesis, esrp1 expression is restricted to a subset of epithelial cells and is associated with splicing of a number of developmentally important genes. Dev Dyn. 2013 Mar;242(3):281-90
All references(39)

Other accession IDs

MGI:1924397