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Dhx35 Gene Detail
Summary
  • Symbol
    Dhx35
  • Name
    DEAH (Asp-Glu-Ala-His) box polypeptide 35
  • Synonyms
    1200009D07Rik, Ddx35
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918965
    NCBI Gene: 71715
Location & Maps
more
  • Sequence Map
    Chr2:158794807-158858214 bp, + strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      63408 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 2, 78.74 cM
  • Mapping Data
    1 experiment
Homology
more
  • Human Ortholog
    DHX35, DEAH-box helicase 35
  • Vertebrate Orthologs
    9
  • Human Ortholog
    DHX35, DEAH-box helicase 35
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C20orf15, DDX35, KAIA0875
  • Links
    NCBI Gene ID: 60625
    neXtProt AC: NX_Q9H5Z1

  • Chr Location
    20q11.23-q12; chr20:38962338-39039723 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 6406
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DHX35
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    1 phenotype from 1 allele in 1 genetic background
    12 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000015943 VEGA Gene Model | MGI Sequence Detail 63408 C57BL/6J ±  kb
transcript OTTMUST00000037882 VEGA | MGI Sequence Detail 3284 Not Applicable  
polypeptide OTTMUSP00000017008 VEGA | MGI Sequence Detail 703 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    780 from dbSNP Build 142
Protein
Information
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  • UniProt
    3 Sequences
  • InterPro Domains
    IPR002464 DNA/RNA helicase, ATP-dependent, DEAH-box type, conserved site
    IPR011709 Domain of unknown function DUF1605
    IPR007502 Helicase-associated domain
    IPR001650 Helicase, C-terminal
    IPR014001 Helicase superfamily 1/2, ATP-binding domain
    IPR027417 P-loop containing nucleoside triphosphate hydrolase
Molecular
Reagents
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  • All nucleic 7
    cDNA 7

    Microarray probesets 3
References
more
  • Summaries
    All 31
    Gene Ontology 2
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
11/22/2016
MGI 6.06
The Jackson Laboratory