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Cdc40 Gene Detail
Summary
  • Symbol
    Cdc40
  • Name
    cell division cycle 40
  • Synonyms
    1200003H23Rik, EHB3, PRP17
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918963
    NCBI Gene: 71713
  • Gene Overview
    MyGene.info: CDC40
Location & Maps
more
  • Sequence Map
    Chr10:40831626-40883143 bp, - strand
  • From Ensembl annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      51518 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 22.06 cM, cytoband B1
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    CDC40, cell division cycle 40
  • Vertebrate Orthologs
    10
  • Human Ortholog
    CDC40, cell division cycle 40
    Orthology source: HomoloGene
  • Synonyms
    EHB3, PRP17, PRPF17
  • Links
    NCBI Gene ID: 51362
    neXtProt AC: NX_O60508

  • Chr Location
    6q21; chr6:110180421-110232232 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 5716
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: CDC40
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    12 phenotype references
  • All Mutations and Alleles
    18
  • Chemically induced (other)
    1
  • Gene trapped
    14
  • Radiation induced
    1
  • Targeted
    2
  • Genomic Mutations
    2 involving Cdc40
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000038446 Ensembl Gene Model | MGI Sequence Detail 51518 C57BL/6J ±  kb
transcript ENSMUST00000044166 Ensembl | MGI Sequence Detail 3361 Not Applicable  
polypeptide ENSMUSP00000044305 Ensembl | MGI Sequence Detail 579 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    430 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 41
    cDNA 40
    Primer pair 1

    Microarray probesets 4
References
more
  • Summaries
    All 32
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 12
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:170300 Chen J, et al., Genome-wide analysis of translation reveals a critical role for deleted in azoospermia-like (Dazl) at the oocyte-to-zygote transition. Genes Dev. 2011 Apr 1;25(7):755-66

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
08/17/2016
MGI 6.05
The Jackson Laboratory