About   Help   FAQ
Dram1 Gene Detail
Summary
  • Symbol
    Dram1
  • Name
    DNA-damage regulated autophagy modulator 1
  • Synonyms
    1200002N14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918962
    NCBI Gene: 71712
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr10:88322801-88364383 bp, - strand
  • From NCBI annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 43.81 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    573 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918962
protein coding gene Chr10:88322801-88379080 (-)
129S1/SvImJ MGP_129S1SvImJ_G0017625
protein coding gene Chr10:89399925-89463235 (-)
A/J MGP_AJ_G0017604
protein coding gene Chr10:86382422-86439018 (-)
AKR/J MGP_AKRJ_G0017562
protein coding gene Chr10:88844034-88899808 (-)
BALB/cJ MGP_BALBcJ_G0017567
protein coding gene Chr10:86665158-86721700 (-)
C3H/HeJ MGP_C3HHeJ_G0017390
protein coding gene Chr10:88816671-88877586 (-)
C57BL/6NJ MGP_C57BL6NJ_G0018024
protein coding gene Chr10:92405808-92474920 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015706
protein coding gene Chr10:82149109-82207261 (-)
CAST/EiJ MGP_CASTEiJ_G0016955
protein coding gene Chr10:88725609-88787105 (-)
CBA/J MGP_CBAJ_G0017359
protein coding gene Chr10:96230104-96303679 (-)
DBA/2J MGP_DBA2J_G0017465
protein coding gene Chr10:85501536-85558072 (-)
FVB/NJ MGP_FVBNJ_G0017457
protein coding gene Chr10:84727408-84784765 (-)
LP/J MGP_LPJ_G0017539
protein coding gene Chr10:90072030-90129900 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0017488
protein coding gene Chr10:97736979-97798516 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0018061
protein coding gene Chr10:88670629-88733791 (-)
PWK/PhJ MGP_PWKPhJ_G0016736
protein coding gene Chr10:85517626-85577228 (-)
SPRET/EiJ MGP_SPRETEiJ_G0016524
protein coding gene Chr10:87405731-87475657 (-)
WSB/EiJ MGP_WSBEiJ_G0017014
protein coding gene Chr10:88646425-88712114 (-)



Homology
more
  • Human Ortholog
    DRAM1, DNA damage regulated autophagy modulator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DRAM1, DNA damage regulated autophagy modulator 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    DRAM
  • Links
    NCBI Gene ID: 55332
    neXtProt AC: NX_Q8N682
    UniProt: Q8N682

  • Chr Location
    12q23.2; chr12:101877327-101923623 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 41255
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: DRAM1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    15 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71712 NCBI Gene Model | MGI Sequence Detail 41583 C57BL/6J ±  kb
transcript NM_027878 RefSeq | MGI Sequence Detail 2807 C57BL/6  
polypeptide Q9DC58 UniProt | EBI | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 23
    cDNA 23

    Microarray probesets 3
References
more
  • Summaries
    All 39
    Gene Ontology 4
    Phenotypes 15
  • Earliest
    J:137335 Roderick TH, Chromosomal inversions in studies of mammalian mutagenesis. Genetics. 1979 May;92(1 Pt 1 Suppl):s121-6
  • Latest
    J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
03/13/2019
MGI 6.13
The Jackson Laboratory