About   Help   FAQ
Dram1 Gene Detail
Summary
  • Symbol
    Dram1
  • Name
    DNA-damage regulated autophagy modulator 1
  • Synonyms
    1200002N14Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918962
    NCBI Gene: 71712
Location & Maps
more
  • Sequence Map
    Chr10:88322804-88379080 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      56277 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 43.81 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    DRAM1, DNA damage regulated autophagy modulator 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    DRAM1, DNA damage regulated autophagy modulator 1
    Orthology source: HGNC, HomoloGene
  • Synonyms
    DRAM
  • Links
    NCBI Gene ID: 55332
    neXtProt AC: NX_Q8N682

  • Chr Location
    12q23.2; chr12:101877327-101923623 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 41255
    1 human;1 mouse;1 rat;1 chimpanzee;1 rhesus macaque;1 cattle;1 dog;1 chicken;1 western clawed frog;1 zebrafish
  • HCOP
    human homology predictions: DRAM1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    13 phenotype references
  • All Mutations and Alleles
    8
  • Chemically induced (other)
    1
  • Gene trapped
    1
  • Targeted
    5
  • Transposon induced
    1
  • Genomic Mutations
    2 involving Dram1
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000023972 VEGA Gene Model | MGI Sequence Detail 56277 C57BL/6J ±  kb
transcript OTTMUST00000058592 VEGA | MGI Sequence Detail 2807 Not Applicable  
polypeptide OTTMUSP00000028415 VEGA | MGI Sequence Detail 238 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    739 from dbSNP Build 142
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000006686 damage-regulated autophagy modulator
  • InterPro Domains
    IPR019402 Frag1/DRAM/Sfk1
Molecular
Reagents
less
  • All nucleic 22
    cDNA 22

    Microarray probesets 3
References
more
  • Summaries
    All 30
    Gene Ontology 3
    Phenotypes 13
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory