Slc46a3 MGI Mouse Gene Detail - MGI:1918956 - solute carrier family 46, member 3

Slc46a3 Gene Detail

Symbol

Slc46a3
Name

solute carrier family 46, member 3
Synonyms

1200006F02Rik

Feature Type

protein coding gene
IDs

MGI:1918956
NCBI Gene: 71706
Gene Overview

MyGene.info: SLC46A3

Sequence Map

Chr5:147878437-147894815 bp, - strand
From VEGA annotation of GRCm38

Mouse Genome Browser
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Sequence

16379 bp ± kb flank
Genome Browsers

VEGA | Ensembl | UCSC | NCBI

Genetic Map

Chromosome 5, 87.58 cM, cytoband G3
Mapping Data

2 experiments

Human Ortholog

SLC46A3, solute carrier family 46 member 3

Vertebrate Orthologs

10

Human Ortholog

SLC46A3, solute carrier family 46 member 3
Orthology source: HomoloGene, HGNC
Synonyms

FKSG16
Links

HGNC:27501

NCBI Gene ID: 283537

neXtProt AC: NX_Q7Z3Q1

UniProt: Q7Z3Q1
Chr Location

13q12.3; chr13:28700080-28719013 (-) GRCh38.p7

HomoloGene

Vertebrate Homology Class 41733
1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
HCOP

human homology predictions: SLC46A3
Gene Tree

Slc46a3

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Phenotype Summary

2 phenotypes from 1 allele in 1 genetic background
6 phenotype references

Phenotype Overview

Blue squares indicate phenotypes directly attributed to mutations/alleles of this gene.

adipose tissue	behavior/neurological	cardiovascular system	cellular	craniofacial	digestive/alimentary system	embryo	endocrine/exocrine glands	growth/size/body	hearing/vestibular/ear	hematopoietic system	homeostasis/metabolism	integument	immune system	limbs/digits/tail	liver/biliary system	mortality/aging	muscle	nervous system	pigmentation	renal/urinary system	reproductive system	respiratory system	skeleton	taste/olfaction	neoplasm	vision/eye

Click cells to view annotations.

All Mutations and Alleles

3
Gene trapped

1
Targeted

2
Incidental Mutations

APF
Find Mice (IMSR)

6 strains or lines available

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All GO Annotations

5
GO References

3

External Resources

FuncBase

Molecular Function

carbohydrate derivative binding	cytoskeletal protein binding	DNA binding	enzyme regulator	hydrolase	ligase	lipid binding	oxidoreductase	receptor	receptor binding	RNA binding	transcription	transferase	transporter

Biological Process

nucleic acid-templated transcription	carbohydrate derivative metabolism	cell death	cell differentiation	cell proliferation	cellular component organization	establishment of localization	homeostatic process	immune system process	lipid metabolic process	protein metabolic process	response to stimulus	signaling	system development

Cellular Component

cell projection	cytoplasmic vesicle	cytoskeleton	cytosol	endoplasmic reticulum	endosome	extracellular region	Golgi apparatus	mitochondrion	non-membrane-bounded organelle	nucleus	organelle envelope	organelle lumen	plasma membrane	synapse	vacuole

Click cells to view annotations.

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Expression Overview

GXD's primary emphasis is on endogenous gene expression during development. Click on grid cells to view annotations.

Blue cells = expressed in wild-type.
Gray triangles = other expression annotations only
(e.g. absence of expression or data from mutants).

early conceptus	embryo ectoderm	embryo endoderm	embryo mesoderm	embryo mesenchyme	extraembryonic component	alimentary system	auditory system	branchial arches	cardiovascular system	connective tissue	endocrine system	exocrine system	hemolymphoid system	integumental system	limbs	liver and biliary system	musculoskeletal system	nervous system	olfactory system	reproductive system	respiratory system	urinary system	visual system

Click cells to view annotations.

Assay Results

38
Tissues

38
cDNA Data

38
Literature Summary

3

Images

Tissue x Stage Matrix

Other Mouse Links

Allen Institute

GEO

Expression Atlas

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Slc46a3 interacts with 142 markers (Mir18b, Mir19a, Mir19b-1, ...) View All

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All Sequences

31
RefSeq

8
UniProt

2
CCDS

CCDS19880.1
UniGene

153218

			Length	Strain/Species	Flank
genomic	OTTMUSG00000028765	VEGA Gene Model \| MGI Sequence Detail	16379	C57BL/6J	± kb
transcript	OTTMUST00000071250	VEGA \| MGI Sequence Detail	2210	Not Applicable
polypeptide	OTTMUSP00000036469	VEGA \| MGI Sequence Detail	460	Not Applicable

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SNPs within 2kb

19 from dbSNP Build 142

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UniProt

2 Sequences
Protein Ontology

PR:000031959 solute carrier family 46 member 3

(term hierarchy)
InterPro Domains

IPR011701 Major facilitator superfamily

IPR020846 Major facilitator superfamily domain

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All nucleic 39

cDNA 38

Primer pair 1

Microarray probesets 4

Summaries

All 33

Developmental Gene Expression 3

Gene Ontology 3

Phenotypes 6
Earliest

J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
Latest

J:236599 Dickinson ME, et al., High-throughput discovery of novel developmental phenotypes. Nature. 2016 Sep 14;537(7621):508-514

Contributing Projects: Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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