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Esm1 Gene Detail
Summary
  • Symbol
    Esm1
  • Name
    endothelial cell-specific molecule 1
  • Synonyms
    0610042H23Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918940
    NCBI Gene: 71690
  • Gene Overview
    MyGene.info: ESM1
  • Alliance
  • Transcription Start Sites
    4 TSS
Location &
Maps
more
  • Sequence Map
    Chr13:113209659-113218098 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 13, 63.93 cM
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918940
protein coding gene Chr13:113209659-113218104 (.)
129S1/SvImJ MGP_129S1SvImJ_G0020950
protein coding gene Chr13:115833722-115842135 (+)
A/J MGP_AJ_G0020900
protein coding gene Chr13:111208081-111216674 (+)
AKR/J MGP_AKRJ_G0020875
protein coding gene Chr13:114552124-114560537 (+)
BALB/cJ MGP_BALBcJ_G0020900
protein coding gene Chr13:111891369-111899782 (+)
C3H/HeJ MGP_C3HHeJ_G0020689
protein coding gene Chr13:114341180-114349593 (+)
C57BL/6NJ MGP_C57BL6NJ_G0021336
protein coding gene Chr13:119262201-119271291 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0018905
protein coding gene Chr13:106495279-106504206 (+)
CAST/EiJ MGP_CASTEiJ_G0020208
protein coding gene Chr13:113990521-113998934 (+)
CBA/J MGP_CBAJ_G0020651
protein coding gene Chr13:123841171-123849584 (+)
DBA/2J MGP_DBA2J_G0020774
protein coding gene Chr13:110912138-110920551 (+)
FVB/NJ MGP_FVBNJ_G0020758
protein coding gene Chr13:109604062-109612607 (+)
LP/J MGP_LPJ_G0020850
protein coding gene Chr13:115878009-115886422 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0020786
protein coding gene Chr13:124129992-124139159 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0021372
protein coding gene Chr13:114032520-114041062 (+)
PWK/PhJ MGP_PWKPhJ_G0019962
protein coding gene Chr13:109673608-109682262 (+)
SPRET/EiJ MGP_SPRETEiJ_G0019783
protein coding gene Chr13:110337102-110345430 (+)
WSB/EiJ MGP_WSBEiJ_G0020266
protein coding gene Chr13:114614563-114622982 (+)



Homology
more
  • Human Ortholog
    ESM1, endothelial cell specific molecule 1
  • Vertebrate Orthologs
    10
  • Human Ortholog
    ESM1, endothelial cell specific molecule 1
    Orthology source: HomoloGene, HGNC
  • Synonyms
    endocan
  • Links
    NCBI Gene ID: 11082
    neXtProt AC: NX_Q9NQ30
    UniProt: Q9NQ30

  • Chr Location
    5q11.2; chr5:54977867-54985586 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 5107
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: ESM1
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    1 phenotype reference
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000042379 Ensembl Gene Model | MGI Sequence Detail 8440 C57BL/6J ±  kb
transcript ENSMUST00000038144 Ensembl | MGI Sequence Detail 2097 Not Applicable  
polypeptide ENSMUSP00000040187 Ensembl | MGI Sequence Detail 184 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000007200 endothelial cell-specific molecule 1
  • InterPro Domains
    IPR038850 Endothelial cell-specific molecule 1
    IPR009030 Growth factor receptor cysteine-rich domain superfamily
    IPR000867 Insulin-like growth factor-binding protein, IGFBP
Molecular
Reagents
less
  • All nucleic 11
    cDNA 9
    Primer pair 1
    Other 1

    Microarray probesets 3
Other
Accession IDs
less
MGI:2145384
References
more
  • Summaries
    All 34
    Developmental Gene Expression 6
    Gene Ontology 5
    Phenotypes 1
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:246913 Zheng X, et al., Murine glomerular transcriptome links endothelial cell-specific molecule-1 deficiency with susceptibility to diabetic nephropathy. PLoS One. 2017;12(9):e0185250

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/13/2018
MGI 6.13
The Jackson Laboratory