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Brox Gene Detail
Summary
  • Symbol
    Brox
  • Name
    BRO1 domain and CAAX motif containing
  • Synonyms
    0610010K06Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918928
    NCBI Gene: 71678
  • Alliance
  • Transcription Start Sites
    2 TSS
Location &
Maps
more
  • Sequence Map
    Chr1:183276352-183297269 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 1, Syntenic
  • Mapping Data
    2 experiments
Strain
Comparison
more
  • SNPs within 2kb
    164 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918928
protein coding gene Chr1:183276342-183297274 (-)
129S1/SvImJ MGP_129S1SvImJ_G0016901
protein coding gene Chr1:189919260-189943057 (-)
A/J MGP_AJ_G0016880
protein coding gene Chr1:182163803-182184386 (-)
AKR/J MGP_AKRJ_G0016845
protein coding gene Chr1:187578466-187603627 (-)
BALB/cJ MGP_BALBcJ_G0016838
protein coding gene Chr1:182806534-182827944 (-)
C3H/HeJ MGP_C3HHeJ_G0016662
protein coding gene Chr1:188378879-188399965 (-)
C57BL/6NJ MGP_C57BL6NJ_G0017301
protein coding gene Chr1:196018135-196040964 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0015008
protein coding gene Chr1:173220511-173241649 (-)
CAST/EiJ MGP_CASTEiJ_G0016245
protein coding gene Chr1:187770181-187791353 (-)
CBA/J MGP_CBAJ_G0016636
protein coding gene Chr1:203321171-203351328 (-)
DBA/2J MGP_DBA2J_G0016742
protein coding gene Chr1:180945569-180966465 (-)
FVB/NJ MGP_FVBNJ_G0016738
protein coding gene Chr1:179078949-179100161 (-)
LP/J MGP_LPJ_G0016817
protein coding gene Chr1:191107889-191130773 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0016770
protein coding gene Chr1:210272408-210292653 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0017338
protein coding gene Chr1:187407049-187427999 (-)
PWK/PhJ MGP_PWKPhJ_G0016032
protein coding gene Chr1:180146405-180167469 (-)
SPRET/EiJ MGP_SPRETEiJ_G0015808
protein coding gene Chr1:186369141-186391527 (-)
WSB/EiJ MGP_WSBEiJ_G0016307
protein coding gene Chr1:187584711-187606655 (-)



Homology
more
  • Human Ortholog
    BROX, BRO1 domain and CAAX motif containing
  • Vertebrate Orthologs
    10
  • Human Ortholog
    BROX, BRO1 domain and CAAX motif containing
    Orthology source: HomoloGene, HGNC
  • Synonyms
    C1orf58
  • Links
    NCBI Gene ID: 148362
    neXtProt AC: NX_Q5VW32
    UniProt: Q5VW32

  • Chr Location
    1q41; chr1:222712553-222735196 (+)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 13499
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: BROX
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    6 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000046836 Ensembl Gene Model | MGI Sequence Detail 20918 C57BL/6J ±  kb
transcript ENSMUST00000163528 Ensembl | MGI Sequence Detail 3413 Not Applicable  
polypeptide ENSMUSP00000132333 Ensembl | MGI Sequence Detail 411 Not Applicable  
For the selected sequence
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 14
    cDNA 14

    Microarray probesets 7
References
more
  • Summaries
    All 29
    Gene Ontology 1
    Phenotypes 6
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-Le-Grand). 1999 Jul;45(5):737-50
  • Latest
    J:166585 Ichioka F, et al., Brox, a novel farnesylated Bro1 domain-containing protein that associates with charged multivesicular body protein 4 (CHMP4). FEBS J. 2008 Feb;275(4):682-92

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB), Gene Ontology (GO)
Citing These Resources
Funding Information
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last database update
10/08/2019
MGI 6.14
The Jackson Laboratory