About   Help   FAQ
Mettl7b Gene Detail
Summary
  • Symbol
    Mettl7b
  • Name
    methyltransferase like 7B
  • Synonyms
    0610006F02Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918914
    NCBI Gene: 71664
Location & Maps
more
  • Sequence Map
    Chr10:128958277-128960988 bp, - strand
  • From NCBI annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      2712 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 10, 77.20 cM, cytoband D3
  • Mapping Data
    3 experiments
Homology
more
  • Human Ortholog
    METTL7B, methyltransferase like 7B
  • Vertebrate Orthologs
    7
  • Human Ortholog
    METTL7B, methyltransferase like 7B
    Orthology source: HGNC, HomoloGene
  • Synonyms
    ALDI
  • Links
    NCBI Gene ID: 196410
    neXtProt AC: NX_Q6UX53

  • Chr Location
    12q13.2; chr12:55681546-55684611 (+)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    2 phenotypes from 1 allele in 1 genetic background
    4 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    3
  • Targeted
    3
  • Incidental Mutations
    APF
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic 71664 NCBI Gene Model | MGI Sequence Detail 2712 C57BL/6J ±  kb
transcript NM_027853 RefSeq | MGI Sequence Detail 1227 C57BL/6  
polypeptide Q9DD20 UniProt | EBI | MGI Sequence Detail 244 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    60 from dbSNP Build 142
Protein
Information
less
  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010353 methyltransferase-like protein 7B
  • EC
  • InterPro Domains
    IPR013216 Methyltransferase type 11
    IPR029063 S-adenosyl-L-methionine-dependent methyltransferase
Molecular
Reagents
less
  • All nucleic 147
    cDNA 147

    Microarray probesets 2
Other
Accession IDs
less
MGI:2143555
References
more
  • Summaries
    All 29
    Developmental Gene Expression 3
    Gene Ontology 4
    Phenotypes 4
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:228563 Koscielny G, et al., The International Mouse Phenotyping Consortium Web Portal, a unified point of access for knockout mice and related phenotyping data. Nucleic Acids Res. 2014 Jan;42(Database issue):D802-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
Warranty Disclaimer & Copyright Notice
Send questions and comments to User Support.
last database update
07/19/2016
MGI 6.04
The Jackson Laboratory