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Ythdf3 Gene Detail
Summary
  • Symbol
    Ythdf3
  • Name
    YTH N6-methyladenosine RNA binding protein 3
  • Synonyms
    9130022A11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918850
    NCBI Gene: 229096
  • Gene Overview
    MyGene.info: YTHDF3
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr3:16183212-16217037 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 3, 4.04 cM
  • Mapping Data
    1 experiment
Strain
Comparison
more
  • SNPs within 2kb
    179 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918850
protein coding gene Chr3:16183141-16217037 (.)
129S1/SvImJ MGP_129S1SvImJ_G0027085
protein coding gene Chr3:13423144-13461869 (+)
A/J MGP_AJ_G0027046
protein coding gene Chr3:13326724-13360457 (+)
AKR/J MGP_AKRJ_G0027015
protein coding gene Chr3:13354492-13389038 (+)
BALB/cJ MGP_BALBcJ_G0027058
protein coding gene Chr3:13070403-13105617 (+)
C3H/HeJ MGP_C3HHeJ_G0026798
protein coding gene Chr3:13456222-13490507 (+)
C57BL/6NJ MGP_C57BL6NJ_G0027502
protein coding gene Chr3:14246443-14283117 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0024863
protein coding gene Chr3:11675800-11705499 (+)
CAST/EiJ MGP_CASTEiJ_G0026254
protein coding gene Chr3:13459672-13495229 (+)
CBA/J MGP_CBAJ_G0026776
protein coding gene Chr3:14515998-14551591 (+)
DBA/2J MGP_DBA2J_G0026910
protein coding gene Chr3:12907591-12942522 (+)
FVB/NJ MGP_FVBNJ_G0026879
protein coding gene Chr3:12650378-12684261 (+)
LP/J MGP_LPJ_G0027022
protein coding gene Chr3:13971898-14011022 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0026899
protein coding gene Chr3:16257496-16298965 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0027561
protein coding gene Chr3:13182587-13217860 (+)
PWK/PhJ MGP_PWKPhJ_G0025987
protein coding gene Chr3:12754769-12788527 (+)
SPRET/EiJ MGP_SPRETEiJ_G0025794
protein coding gene Chr3:12996110-13032080 (+)
WSB/EiJ MGP_WSBEiJ_G0026327
protein coding gene Chr3:13218362-13261903 (+)



Homology
more
  • Human Ortholog
    YTHDF3, YTH N6-methyladenosine RNA binding protein 3
  • Vertebrate Orthologs
    8
  • Human Ortholog
    YTHDF3, YTH N6-methyladenosine RNA binding protein 3
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 253943
    neXtProt AC: NX_Q7Z739
    UniProt: Q7Z739

  • Chr Location
    8q12.3; chr8:63168553-63212788 (+)  GRCh38.p7

Human Diseases
less
  • References
    1 with disease annotations
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    7 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
  • cDNA Data
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000047213 Ensembl Gene Model | MGI Sequence Detail 33826 C57BL/6J ±  kb
transcript ENSMUST00000108346 Ensembl | MGI Sequence Detail 4929 Not Applicable  
polypeptide ENSMUSP00000103983 Ensembl | MGI Sequence Detail 596 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    4 Sequences
  • InterPro Domains
    IPR007275 YTH domain
Molecular
Reagents
less
  • All nucleic 173
    cDNA 173

    Microarray probesets 8
References
more
  • Summaries
    All 28
    Diseases 1
    Gene Ontology 3
    Phenotypes 7
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:142754 Hansen GM, et al., Large-scale gene trapping in C57BL/6N mouse embryonic stem cells. Genome Res. 2008 Oct;18(10):1670-9

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory