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Mtrf1l Gene Detail
Summary
  • Symbol
    Mtrf1l
  • Name
    mitochondrial translational release factor 1-like
  • Synonyms
    9130004K12Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918830
    NCBI Gene: 108853
Location & Maps
more
  • Sequence Map
    Chr10:5811887-5823910 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      12024 bp   ±  kb flank

  • Genome Browsers
Homology
more
  • Human Ortholog
    MTRF1L, mitochondrial translational release factor 1 like
  • Vertebrate Orthologs
    10
  • Human Ortholog
    MTRF1L, mitochondrial translational release factor 1 like
    Orthology source: HomoloGene
  • Synonyms
    HMRF1L, MRF1L, mtRF1a
  • Links
    NCBI Gene ID: 54516
    neXtProt AC: NX_Q9UGC7

  • Chr Location
    6q25-q26; chr6:152987366-153002815 (-)  GRCh38.p2

Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    3 phenotypes from 1 allele in 1 genetic background
    3 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryogenesis
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
tumorigenesis
vision/eye

Click cells to view annotations.
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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  • cDNA Data
Interactions
less
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000022750 VEGA Gene Model | MGI Sequence Detail 12024 C57BL/6J ±  kb
transcript OTTMUST00000054604 VEGA | MGI Sequence Detail 2588 Not Applicable  
polypeptide OTTMUSP00000026081 VEGA | MGI Sequence Detail 373 Not Applicable  
For the selected sequence
Polymorphisms
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  • SNPs within 2kb
    122 from dbSNP Build 137
Protein
Information
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  • UniProt
    1 Sequence
  • Protein Ontology
    PR:000010749 peptide chain release factor 1-like, mitochondrial
  • InterPro Domains
    IPR014720 Double-stranded RNA-binding domain
    IPR005139 Peptide chain release factor
    IPR000352 Peptide chain release factor class I/class II
Molecular
Reagents
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  • All nucleic 13
    cDNA 13

    Microarray probesets 2
References
more
  • Summaries
    All 24
    Gene Ontology 5
    Phenotypes 3
  • Earliest
    J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
  • Latest
    J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
02/02/2016
MGI 6.02
The Jackson Laboratory