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Tcta Gene Detail
Summary
  • Symbol
    Tcta
  • Name
    T cell leukemia translocation altered gene
  • Synonyms
    9130410M22Rik, C85065, Tctal
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918829
    NCBI Gene: 102791
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108180157-108183174 bp, - strand
    From NCBI annotation of GRCm39
  • View this region in JBrowse
  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918829
protein coding gene Chr9:108180157-108183359 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035291
protein coding gene Chr9:110248319-110251521 (-)
A/J MGP_AJ_G0035270
protein coding gene Chr9:106211629-106214788 (-)
AKR/J MGP_AKRJ_G0035202
protein coding gene Chr9:108861889-108865088 (-)
BALB/cJ MGP_BALBcJ_G0035264
protein coding gene Chr9:105909459-105912670 (-)
C3H/HeJ MGP_C3HHeJ_G0034974
protein coding gene Chr9:109258463-109261689 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035784
protein coding gene Chr9:113234139-113239306 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032682
protein coding gene Chr9:103643559-103647316 (-)
CAST/EiJ MGP_CASTEiJ_G0034285
protein coding gene Chr9:109231031-109234230 (-)
CBA/J MGP_CBAJ_G0034942
protein coding gene Chr9:117244019-117247223 (-)
DBA/2J MGP_DBA2J_G0035103
protein coding gene Chr9:105669054-105672317 (-)
FVB/NJ MGP_FVBNJ_G0035051
protein coding gene Chr9:104434344-104437535 (-)
LP/J MGP_LPJ_G0035179
protein coding gene Chr9:110447850-110451052 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035090
protein coding gene Chr9:118826945-118833672 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035805
protein coding gene Chr9:109157728-109160920 (-)
PWK/PhJ MGP_PWKPhJ_G0033992
protein coding gene Chr9:105996065-105999204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033828
protein coding gene Chr9:109215253-109218745 (-)
WSB/EiJ MGP_WSBEiJ_G0034406
protein coding gene Chr9:109030502-109033661 (-)



Homology
more
  • Human Ortholog
    TCTA, T cell leukemia translocation altered
  • Vertebrate Orthologs
    3
Vertebrate Orthology Source
Alliance of Genome Resources
  • Human Ortholog
    TCTA, T cell leukemia translocation altered
  • Links
    NCBI Gene ID: 6988
    neXtProt AC: NX_P57738
    UniProt: P57738

  • Chr Location
    3p21.31; chr3:49412212-49416476 (+)  GRCh38

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell differentiation
cell population proliferation
cellular component organization
DNA-templated transcription
establishment of localization
homeostatic process
immune system process
lipid metabolic process
programmed cell death
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
protein-containing complex
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic 102791 NCBI Gene Model | MGI Sequence Detail 3018 C57BL/6J ±  kb
transcript NM_133986 RefSeq | MGI Sequence Detail 1653 ZRU/MplStud  
polypeptide Q8VEA7 UniProt | EBI | MGI Sequence Detail 122 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016206 T-cell leukemia translocation-altered gene protein
  • InterPro Domains
    IPR016560 T-cell leukemia translocation-altered gene protein
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 10

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-33661, MGI:105981, MGI:2143328, MGI:2143421
References
more
  • Summaries
    All 29
    Developmental Gene Expression 2
    Gene Ontology 3
    Phenotypes 3
  • Earliest
    J:24929 Aplan PD, et al., Cloning and characterization of TCTA, a gene located at the site of a t(1;3) translocation. Cancer Res. 1995 May 1;55(9):1917-21
  • Latest
    J:153498 Diez-Roux G, et al., A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. 2011;9(1):e1000582

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Funding Information
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last database update
04/09/2024
MGI 6.23
The Jackson Laboratory