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Tcta Gene Detail
Summary
  • Symbol
    Tcta
  • Name
    T cell leukemia translocation altered gene
  • Synonyms
    9130410M22Rik, C85065, Tctal
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918829
    NCBI Gene: 102791
  • Alliance
  • Transcription Start Sites
    3 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:108302958-108306160 bp, - strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 59.20 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    4 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918829
protein coding gene Chr9:108302955-108306160 (-)
129S1/SvImJ MGP_129S1SvImJ_G0035291
protein coding gene Chr9:110248319-110251521 (-)
A/J MGP_AJ_G0035270
protein coding gene Chr9:106211629-106214788 (-)
AKR/J MGP_AKRJ_G0035202
protein coding gene Chr9:108861889-108865088 (-)
BALB/cJ MGP_BALBcJ_G0035264
protein coding gene Chr9:105909459-105912670 (-)
C3H/HeJ MGP_C3HHeJ_G0034974
protein coding gene Chr9:109258463-109261689 (-)
C57BL/6NJ MGP_C57BL6NJ_G0035784
protein coding gene Chr9:113234139-113239306 (-)
CAROLI/EiJ MGP_CAROLIEiJ_G0032682
protein coding gene Chr9:103643559-103647316 (-)
CAST/EiJ MGP_CASTEiJ_G0034285
protein coding gene Chr9:109231031-109234230 (-)
CBA/J MGP_CBAJ_G0034942
protein coding gene Chr9:117244019-117247223 (-)
DBA/2J MGP_DBA2J_G0035103
protein coding gene Chr9:105669054-105672317 (-)
FVB/NJ MGP_FVBNJ_G0035051
protein coding gene Chr9:104434344-104437535 (-)
LP/J MGP_LPJ_G0035179
protein coding gene Chr9:110447850-110451052 (-)
NOD/ShiLtJ MGP_NODShiLtJ_G0035090
protein coding gene Chr9:118826945-118833672 (-)
NZO/HlLtJ MGP_NZOHlLtJ_G0035805
protein coding gene Chr9:109157728-109160920 (-)
PWK/PhJ MGP_PWKPhJ_G0033992
protein coding gene Chr9:105996065-105999204 (-)
SPRET/EiJ MGP_SPRETEiJ_G0033828
protein coding gene Chr9:109215253-109218745 (-)
WSB/EiJ MGP_WSBEiJ_G0034406
protein coding gene Chr9:109030502-109033661 (-)



Homology
more
  • Human Ortholog
    TCTA, T cell leukemia translocation altered
  • Vertebrate Orthologs
    9
  • Human Ortholog
    TCTA, T cell leukemia translocation altered
    Orthology source: HomoloGene, HGNC
  • Links
    NCBI Gene ID: 6988
    neXtProt AC: NX_P57738
    UniProt: P57738

  • Chr Location
    3p21.31; chr3:49412206-49416476 (+)  GRCh38.p7

Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    3 phenotype references
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
less
Sequences &
Gene Models
less
Representative SequencesLengthStrain/SpeciesFlank
genomic ENSMUSG00000039461 Ensembl Gene Model | MGI Sequence Detail 3203 C57BL/6J ±  kb
transcript ENSMUST00000195615 Ensembl | MGI Sequence Detail 597 Not Applicable  
polypeptide ENSMUSP00000141592 Ensembl | MGI Sequence Detail 133 Not Applicable  
For the selected sequence
Protein
Information
less
  • UniProt
    3 Sequences
  • Protein Ontology
    PR:000016206 T-cell leukemia translocation-altered gene protein
  • InterPro Domains
    IPR016560 T-cell leukemia translocation-altered gene protein
Molecular
Reagents
less
  • All nucleic 11
    Genomic 1
    cDNA 10

    Microarray probesets 6
Other
Accession IDs
less
MGD-MRK-33661, MGI:105981, MGI:2143328, MGI:2143421
References
more
  • Summaries
    All 30
    Developmental Gene Expression 2
    Gene Ontology 4
    Phenotypes 3
  • Earliest
    J:24929 Aplan PD, et al., Cloning and characterization of TCTA, a gene located at the site of a t(1;3) translocation. Cancer Res. 1995 May 1;55(9):1917-21
  • Latest
    J:265628 Gaudet P, et al., Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief Bioinform. 2011 Sep;12(5):449-62

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/06/2018
MGI 6.13
The Jackson Laboratory