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Clmp Gene Detail
Summary
  • Symbol
    Clmp
  • Name
    CXADR-like membrane protein
  • Synonyms
    9030425E11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918816
    NCBI Gene: 71566
  • Alliance
  • Transcription Start Sites
    6 TSS
Location &
Maps
more
  • Sequence Map
    Chr9:40685962-40785319 bp, + strand
  • From Ensembl annotation of GRCm38

    View this region in JBrowse

  • Genome Browsers
  • Genetic Map
    Chromosome 9, 21.42 cM
  • Mapping Data
    3 experiments
Strain
Comparison
more
  • SNPs within 2kb
    1260 from dbSNP Build 142
  • Strain Annotations
    18
For selected strains:
Strain Gene Model ID Feature Type Coordinates Select Strains
C57BL/6J MGI_C57BL6J_1918816
protein coding gene Chr9:40685962-40785553 (+)
129S1/SvImJ MGP_129S1SvImJ_G0034669
protein coding gene Chr9:38911750-39020222 (+)
A/J MGP_AJ_G0034649
protein coding gene Chr9:37892510-38018311 (+)
AKR/J MGP_AKRJ_G0034575
protein coding gene Chr9:38629325-38738222 (+)
BALB/cJ MGP_BALBcJ_G0034640
protein coding gene Chr9:37664454-37766357 (+)
C3H/HeJ MGP_C3HHeJ_G0034351
protein coding gene Chr9:39145834-39253698 (+)
C57BL/6NJ MGP_C57BL6NJ_G0035163
protein coding gene Chr9:40140157-40253720 (+)
CAROLI/EiJ MGP_CAROLIEiJ_G0032077
protein coding gene Chr9:37546072-37646880 (+)
CAST/EiJ MGP_CASTEiJ_G0033674
protein coding gene Chr9:38873563-38978691 (+)
CBA/J MGP_CBAJ_G0034324
protein coding gene Chr9:41537899-41656323 (+)
DBA/2J MGP_DBA2J_G0034483
protein coding gene Chr9:37855842-37958663 (+)
FVB/NJ MGP_FVBNJ_G0034423
protein coding gene Chr9:37078479-37181189 (+)
LP/J MGP_LPJ_G0034564
protein coding gene Chr9:39196933-39302326 (+)
NOD/ShiLtJ MGP_NODShiLtJ_G0034467
protein coding gene Chr9:43585140-43698471 (+)
NZO/HlLtJ MGP_NZOHlLtJ_G0035182
protein coding gene Chr9:38549812-38656934 (+)
PWK/PhJ MGP_PWKPhJ_G0033379
protein coding gene Chr9:37663904-37763224 (+)
SPRET/EiJ MGP_SPRETEiJ_G0033215
protein coding gene Chr9:38789603-38891572 (+)
WSB/EiJ MGP_WSBEiJ_G0033787
protein coding gene Chr9:38571905-38684605 (+)



Homology
more
  • Human Ortholog
    CLMP, CXADR like membrane protein
  • Vertebrate Orthologs
    11
  • Human Ortholog
    CLMP, CXADR like membrane protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    ACAM, ASAM, CSBM, CSBS
  • Links
    NCBI Gene ID: 79827
    neXtProt AC: NX_Q9H6B4
    UniProt: Q9H6B4

  • Chr Location
    11q24.1; chr11:123072006-123195305 (-)  GRCh38.p7

  • HomoloGene
    Vertebrate Homology Class 11705
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 chicken;2 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: CLMP
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
less
  • Phenotype Summary
    27 phenotypes from 3 alleles in 3 genetic backgrounds
    10 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
immune system
integument
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
neoplasm
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
vision/eye

Click cells to view annotations.
Mice homozygous for a targeted null allele exhibit reduced viability, bilateral hydronephrosis, increased mean systolic blood pressure, and exhibit several blood chemistry and neurological anomalies. Null mice are samller than controls.
Gene Ontology
(GO)
Classifications
less
  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
RNA binding
signaling receptor activity
signaling receptor binding
transcription
transferase
transporter
Biological Process

carbohydrate derivative metabolism
cell death
cell differentiation
cell population proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
nucleic acid-templated transcription
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
less
Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
  • Comparison Matrix
  • Interactions
    less
    Sequences &
    Gene Models
    less
    Representative SequencesLengthStrain/SpeciesFlank
    genomic ENSMUSG00000032024 Ensembl Gene Model | MGI Sequence Detail 99358 C57BL/6J ±  kb
    transcript ENSMUST00000034522 Ensembl | MGI Sequence Detail 4154 Not Applicable  
    polypeptide ENSMUSP00000034522 Ensembl | MGI Sequence Detail 373 Not Applicable  
    For the selected sequence
    Protein
    Information
    less
    Molecular
    Reagents
    less
    • All nucleic 64
      cDNA 64

      Microarray probesets 5
    Other
    Accession IDs
    less
    MGI:2143334
    References
    more
    • Summaries
      All 38
      Developmental Gene Expression 4
      Gene Ontology 3
      Phenotypes 10
    • Earliest
      J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
    • Latest
      J:258315 Langhorst H, et al., The IgCAM CLMP regulates expression of Connexin43 and Connexin45 in intestinal and ureteral smooth muscle contraction in mice. Dis Model Mech. 2018 Feb 22;11(2)

    Contributing Projects:
    Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO)
    Citing These Resources
    Funding Information
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    last database update
    05/14/2019
    MGI 6.14
    The Jackson Laboratory