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Piezo2
Gene Detail
Symbol

Name
ID
Piezo2
piezo-type mechanosensitive ion channel component 2
MGI:1918781
Synonyms
9030411M15Rik, 9430028L06Rik, Fam38b, Fam38b2, Piezo2
Feature Type
protein coding gene
Genetic Map
Chromosome 18
35.95 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:63010213-63387183 bp, - strand
From VEGA annotation of GRCm38

  376971 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49695  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

HCOP human homology predictions: PIEZO2
Gene Tree: Piezo2

Human
homologs
PIEZO2, piezo-type mechanosensitive ion channel component 2
Orthology source: HomoloGene

IDs:
NCBI Gene ID: 63895
neXtProt AC: NX_Q9H5I5

Human Synonyms: C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS

Human Chr (Location): 18p11.22; chr18:10670134-11148762 (-)  GRCh38.p2

Disease Associations: (3) Diseases Associated with Human PIEZO2

Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from APF , CvDC )
Interactions
Piezo2 interacts with 284 markers (Mir7-1, Mir15a, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (15 annotations)
Process cation transmembrane transport, cation transport, ...
Component integral component of membrane, membrane, ...
Function cation channel activity, mechanically-gated ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(27)
Other mouse links: GEO   Expression Atlas
Other vertebrate links: Xenbase piezo2    NEW 
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(3)
Other database
links
VEGA Gene Model OTTMUSG00000028308 (Evidence)
Ensembl Gene Model ENSMUSG00000041482 (Evidence)
Entrez Gene 667742 (Evidence)
UniGene 158720
DFCI TC1586005, TC1599503, TC1594974, TC1591558, TC1613491, TC1611172, TC1617260
DoTS DT.91562897, DT.91309486, DT.87039602, DT.55110396, DT.101705574, DT.94250097, DT.97348317
NIA Mouse Gene Index U066865, U038487
Consensus CDS Project CCDS29296.1
International Mouse Phenotyping Consortium Status Piezo2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028308 VEGA Gene Model | MGI Sequence Detail 376971 C57BL/6J ±  kb
transcript OTTMUST00000070148 VEGA | MGI Sequence Detail 10724 Not Applicable 
polypeptide OTTMUSP00000035722 VEGA | MGI Sequence Detail 2824 Not Applicable 

For the selected sequences
All sequences(87) RefSeq(18) UniProt(8)
Polymorphisms
SNPs within 2kb(2902 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2904)
Protein-related
information
ResourceIDDescription
InterPro IPR027272 Piezo family
Protein Ontology PR:000032708 piezo-type mechanosensitive ion channel component 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:219613 Schrenk-Siemens K, et al., PIEZO2 is required for mechanotransduction in human stem cell-derived touch receptors. Nat Neurosci. 2015 Jan;18(1):10-6
All references(32)
Other
accession IDs
MGI:2442541

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
07/21/2015
MGI 5.22
The Jackson Laboratory