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Piezo2
Gene Detail
Symbol

Name
ID
Piezo2
piezo-type mechanosensitive ion channel component 2
MGI:1918781
Synonyms
9030411M15Rik, 9430028L06Rik, Fam38b, Fam38b2, Piezo2
Feature Type
protein coding gene
Genetic Map
Chromosome 18
35.95 cM, cytoband D3
Detailed Genetic Map ± 1 cM


Mapping data(2)
Sequence Map
Chr18:63010213-63387183 bp, - strand
From VEGA annotation of GRCm38

  376971 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:49695  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 chimpanzee; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 1 zebrafish

Gene Tree: Piezo2

Human
homologs
Human Homolog PIEZO2, piezo-type mechanosensitive ion channel component 2
NCBI Gene ID 63895
neXtProt AC  NX_Q9H5I5
Human Synonyms  C18orf30, C18orf58, DA3, DA5, FAM38B, FAM38B2, HsT748, HsT771, MWKS
Human Chr (Location)  18p11.22; chr18:10670247-11148762 (-)  GRCh38
Disease Associations  (3) Diseases Associated with Human PIEZO2
Mutations,
alleles, and
phenotypes
All mutations/alleles(5) : Targeted(5)
Incidental mutations (data from APF )
Interactions
Piezo2 interacts with 285 markers (Mir7-1, Mir15a, Mir22, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (14 annotations)
Process cation transmembrane transport, cation transport, ...
Component integral component of membrane, membrane, ...
Function cation channel activity, mechanically-gated ion channel activity, ...
External Resources: FuncBase
Expression
Literature Summary: (1 records)
cDNA source data(27)
External Resources: GEO   Expression Atlas
Molecular
reagents
All nucleic(28) cDNA(28)
Microarray probesets(3)
Other database
links
VEGA Gene ModelOTTMUSG00000028308 (Evidence)
Ensembl Gene ModelENSMUSG00000041482 (Evidence)
Entrez Gene667742 (Evidence)
UniGene158720
DFCITC1586005, TC1591558, TC1594974, TC1599503, TC1611172, TC1613491, TC1617260
DoTSDT.101705574, DT.55110396, DT.87039602, DT.91309486, DT.91562897, DT.94250097, DT.97348317
NIA Mouse Gene IndexU038487, U066865
Consensus CDS ProjectCCDS29296.1
International Mouse Knockout Project StatusPiezo2
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000028308 VEGA Gene Model | MGI Sequence Detail 376971 C57BL/6J ±  kb
transcript OTTMUST00000070148 VEGA | MGI Sequence Detail 10724 Not Applicable 
polypeptide OTTMUSP00000035722 VEGA | MGI Sequence Detail 2824 Not Applicable 

For the selected sequences
All sequences(89) RefSeq(20) UniProt(8)
Polymorphisms
SNPs within 2kb(2902 from dbSNP Build 137)    SNPs within 2kb including multiple locations(2904)
Protein-related
information
ResourceIDDescription
InterPro IPR027272 Piezo family
Protein Ontology PR:000032708 piezo-type mechanosensitive ion channel component 2
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:213252 Maksimovic S, et al., Epidermal Merkel cells are mechanosensory cells that tune mammalian touch receptors. Nature. 2014 May 29;509(7502):617-21
All references(31)
Other
accession IDs
MGI:2442541

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
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last database update
10/08/2014
MGI 5.20
The Jackson Laboratory