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Kazn Gene Detail
Summary
  • Symbol
    Kazn
  • Name
    kazrin, periplakin interacting protein
  • Synonyms
    2310007B04Rik, 9030409G11Rik
  • Feature Type
    protein coding gene
  • IDs
    MGI:1918779
    NCBI Gene: 71529
Location & Maps
more
  • Sequence Map
    Chr4:142102390-142239401 bp, - strand
  • From VEGA annotation of GRCm38

    Mouse Genome Browser

  • Download
    Sequence
      137012 bp   ±  kb flank

  • Genome Browsers
  • Genetic Map
    Chromosome 4, 75.46 cM
  • Mapping Data
    2 experiments
Homology
more
  • Human Ortholog
    KAZN, kazrin, periplakin interacting protein
  • Vertebrate Orthologs
    9
  • Human Ortholog
    KAZN, kazrin, periplakin interacting protein
    Orthology source: HomoloGene, HGNC
  • Synonyms
    KAZ
  • Links
    NCBI Gene ID: 23254
    neXtProt AC: NX_Q674X7

  • Chr Location
    1p36.21; chr1:13893515-15118048 (+)  GRCh38.p2

  • HomoloGene
    Vertebrate Homology Class 16235
    1 human;1 mouse;1 rat;1 chimpanzee;1 cattle;1 dog;1 zebrafish;1 frog, western clawed;1 macaque, rhesus
  • HCOP
    human homology predictions: KAZN
  • Gene Tree
Mutations,
Alleles, and
Phenotypes
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  • Phenotype Summary
    6 phenotypes from 3 alleles in 3 genetic backgrounds
    16 phenotype references
Phenotype Overview

adipose tissue
behavior/neurological
cardiovascular system
cellular
craniofacial
digestive/alimentary system
embryo
endocrine/exocrine glands
growth/size/body
hearing/vestibular/ear
hematopoietic system
homeostasis/metabolism
integument
immune system
limbs/digits/tail
liver/biliary system
mortality/aging
muscle
nervous system
pigmentation
renal/urinary system
reproductive system
respiratory system
skeleton
taste/olfaction
neoplasm
vision/eye

Click cells to view annotations.
  • All Mutations and Alleles
    149
  • Chemically induced (other)
    1
  • Gene trapped
    142
  • Targeted
    6
  • Genomic Mutations
    2 involving Kazn
  • Incidental Mutations
Gene Ontology
(GO)
Classifications
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  • All GO Annotations
  • GO References
Molecular Function

carbohydrate derivative binding
cytoskeletal protein binding
DNA binding
enzyme regulator
hydrolase
ligase
lipid binding
oxidoreductase
receptor
receptor binding
RNA binding
transcription
transferase
transporter
Biological Process

nucleic acid-templated transcription
carbohydrate derivative metabolism
cell death
cell differentiation
cell proliferation
cellular component organization
establishment of localization
homeostatic process
immune system process
lipid metabolic process
protein metabolic process
response to stimulus
signaling
system development
Cellular Component

cell projection
cytoplasmic vesicle
cytoskeleton
cytosol
endoplasmic reticulum
endosome
extracellular region
Golgi apparatus
mitochondrion
non-membrane-bounded organelle
nucleus
organelle envelope
organelle lumen
plasma membrane
synapse
vacuole
Click cells to view annotations.
Expression
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Expression Overview

early conceptus
embryo ectoderm
embryo endoderm
embryo mesoderm
embryo mesenchyme
extraembryonic component
alimentary system
auditory system
branchial arches
cardiovascular system
connective tissue
endocrine system
exocrine system
hemolymphoid system
integumental system
limbs
liver and biliary system
musculoskeletal system
nervous system
olfactory system
reproductive system
respiratory system
urinary system
visual system
Click cells to view annotations.


  • Assay Results
  • Tissues
  • cDNA Data
  • Literature Summary
Interactions
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Sequences &
Gene Models
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Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000010182 VEGA Gene Model | MGI Sequence Detail 137012 C57BL/6J ±  kb
transcript OTTMUST00000023667 VEGA | MGI Sequence Detail 4499 Not Applicable  
polypeptide OTTMUSP00000010817 VEGA | MGI Sequence Detail 699 Not Applicable  
For the selected sequence
Polymorphisms
less
  • SNPs within 2kb
    1891 from dbSNP Build 142
Protein
Information
less
Molecular
Reagents
less
  • All nucleic 57
    cDNA 52
    Primer pair 5

    Microarray probesets 5
Other
Accession IDs
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MGI:1916735, MGI:2140216, MGI:2140351, MGI:2140553
References
more
  • Summaries
    All 40
    Developmental Gene Expression 5
    Gene Ontology 2
    Phenotypes 16
  • Earliest
    J:93290 Araki K, et al., Exchangeable gene trap using the Cre/mutated lox system. Cell Mol Biol (Noisy-le-grand). 1999 Jul;45(5):737-50
  • Latest
    J:205051 Miller JA, et al., Conserved molecular signatures of neurogenesis in the hippocampal subgranular zone of rodents and primates. Development. 2013 Nov;140(22):4633-44

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
11/29/2016
MGI 6.06
The Jackson Laboratory