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Grap
Gene Detail
Symbol

Name
ID
Grap
GRB2-related adaptor protein
MGI:1918770
Synonyms
8430435N19Rik
Feature Type
protein coding gene
Genetic Map
Chromosome 11
37.96 cM, cytoband B2
Detailed Genetic Map ± 1 cM


Mapping data(3)
Sequence Map
Chr11:61653265-61672784 bp, + strand
From VEGA annotation of GRCm38

  19520 bp   ±  kb flank

VEGA Genome Browser | Ensembl Genome Browser | UCSC Browser | NCBI Map Viewer


Mouse Genome Browser
Vertebrate
homology
HomoloGene:4822  Vertebrate Homology Class
1 human; 1 mouse; 1 rat; 1 rhesus macaque; 1 cattle; 1 dog; 1 chicken; 1 western clawed frog; 2 zebrafish

Gene Tree: Grap

Human
homologs
Human Homolog GRAP, GRB2-related adaptor protein
NCBI Gene ID 10750
neXtProt AC  NX_Q13588
Human Chr (Location)  17p11.2; chr17:19020656-19047023 (-)  GRCh38
Mutations,
alleles, and
phenotypes
All mutations/alleles(3) : Targeted(3)
Incidental mutations (data from Mutagenetix , APF )
 
Mice homozygous for disruptions in this gene display a greater proliferative T cell response to TCR stimulation. In all other respects, they are normal.
 
Interactions
Grap interacts with 99 markers (Mir7-1, Mir7-2, Mir7b, ...)
Gene Ontology
(GO)
classifications
All GO classifications: (3 annotations)
Process biological_process
Component cellular_component
Function molecular_function
External Resources: FuncBase
Expression
cDNA source data(13)
External Resources: Allen Institute   GEO   Expression Atlas
Molecular
reagents
All nucleic(14) Genomic(1) cDNA(13)
Microarray probesets(2)
Other database
links
VEGA Gene ModelOTTMUSG00000005843 (Evidence)
Ensembl Gene ModelENSMUSG00000004837 (Evidence)
Entrez Gene71520 (Evidence)
UniGene202760
DFCITC1728170, TC1582801
DoTSDT.55273993, DT.101371203, DT.94233790
Consensus CDS ProjectCCDS24817.1
International Mouse Knockout Project StatusGrap
Sequences
Representative SequencesLengthStrain/SpeciesFlank
genomic OTTMUSG00000005843 VEGA Gene Model | MGI Sequence Detail 19520 C57BL/6J ±  kb
transcript OTTMUST00000012997 VEGA | MGI Sequence Detail 1662 Not Applicable 
polypeptide OTTMUSP00000006043 VEGA | MGI Sequence Detail 217 Not Applicable 

For the selected sequences
All sequences(23) RefSeq(2) UniProt(1)
Polymorphisms
SNPs within 2kb(183 from dbSNP Build 137)
Protein-related
information
ResourceIDDescription
InterPro IPR000980 SH2 domain
InterPro IPR001452 Src homology-3 domain
InterPro IPR011511 Variant SH3
Protein Ontology PR:000008219 GRB2-related adapter protein
References
(Earliest) J:65060 Kawai J, et al., Functional annotation of a full-length mouse cDNA collection. Nature. 2001 Feb 8;409(6821):685-90
(Latest) J:173534 Skarnes WC, et al., A conditional knockout resource for the genome-wide study of mouse gene function. Nature. 2011 Jun 16;474(7351):337-42
All references(27)
Other
accession IDs
MGI:2144614

Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Tumor Biology (MTB), Gene Ontology (GO), MouseCyc
Citing These Resources
Funding Information
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last database update
12/09/2014
MGI 5.20
The Jackson Laboratory